5 Fluorouracil

LE WE PMID CA

5 Fluorouracil

Dihydropyrimidine dehydrogenase deficiency

DNA (Repair and Toxicology)

1999 1	5-fluorouracil-induced small bowel toxicity in patients with colorectal carcinoma. [10506695] Cancer 86(7): 1129-34 (1999)
1999 2	Dihydropyrimidine dehydrogenase: its role in 5-fluorouracil clinical toxicity and tumor resistance. [10537327] Clin Cancer Res 5(10): 2672-3 (1999)
1999 3	Dihydropyrimidine dehydrogenase activity: prognostic partner of 5-fluorouracil? [10473070] Clin Cancer Res 5(8): 1947-9 (1999)
2001 4	From 5 fluorouracil to the new oral fluoropyrimidines: a brief overview of four decades of clinical investigations. [11344842] Isr Med Assoc J 3(4): 278-81 (2001)
2009 5	Participation of DNA repair in the response to 5-fluorouracil. [18979208] Cell Mol Life Sci 66(5): 788-99 (2009)
2008 6	Can inhibiting dihydropyrimidine dehydrogenase limit hand-foot syndrome caused by fluoropyrimidines? [18172246] Clin Cancer Res 14(1): 8-13 (2008)
2009 7	Pharmacokinetically guided dose adjustment of 5-fluorouracil: a rational approach to improving therapeutic outcomes. [19841331] J Natl Cancer Inst 101(22): 1543-52 (2009)
2002 8	Thymidylate synthase: a critical target for cancer chemotherapy. [12450420] Clin Colorectal Cancer 1(4): 220-9 (2002)
2002 9	Capecitabine (Xeloda): from the laboratory to the patient's home. [12453332] Clin Colorectal Cancer 2(1): 16-23 (2002)
2004 10	Dihydropyrimidine dehydrogenase deficiency, a pharmacogenetic syndrome associated with potentially life-threatening toxicity following 5-fluorouracil administration. [15377401] Clin Colorectal Cancer 4(3): 181-9 (2004)
2004 11	Dihydopyrimidine dehydrogenase: a critical molecular biomarker for 5-Fluorouracil toxicity. [15377397] Clin Colorectal Cancer 4(3): 150 (2004)
2011 12	Dihydropyrimidine dehydrogenase gene as a major predictor of severe 5-fluorouracil toxicity. [21919607] Pharmacogenomics 12(9): 1321-36 (2011)

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All Medline data shown were primarily retrieved from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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