Arsenic trioxide ttROS

LE WE PMID CA

Arsenic trioxide ttROS

222

Arsentrioxid ttROS

17 N allylamino 17 demethoxygeldanamycin

Apoptosis

Arsenic trioxide ttROS

Bongkrekic acid ttMitochondrial Permaeability Transition

Caspase8

CD95 FAS Apo1

Ceramide

EIF2AK3 PERK

ERS UFR (Pharmacology)

Fenretinide

Interleukin24 MDA7

Kidney (Neoplasia RCC)

Leukemia (acute promyelocytic)

Mitochondria (Permeability transition)

Neoplasia (Oncolytic virus)

NSC656240 ttRedox

PK11195 ttRedox

2008 1	Arsenic trioxide: safety issues and their management. [18298894] Acta Pharmacol Sin 29(3): 296-304 (2008)
1999 2	Arsenic trioxide, a novel mitochondriotoxic anticancer agent? [10328097] J Natl Cancer Inst 91(9): 743-5 (1999)
2002 3	Mechanisms of action of arsenic trioxide. [12124315] Cancer Res 62(14): 3893-903 (2002)
2001 4	Arsenic trioxide, a therapeutic agent for APL. [11704843] Oncogene 20(49): 7146-53 (2001)
2004 5	Arsenic trioxide: expanding roles for an ancient drug? [15269784] Leukemia 18(9): 1457-9 (2004)
2003 6	Opportunities for Trisenox (arsenic trioxide) in the treatment of myelodysplastic syndromes. [12886236] Leukemia 17(8): 1499-507 (2003)
2005 7	Arsenic trioxide in the treatment of acute promyelocytic leukemia. A review of current evidence. [16154847] Haematologica 90(9): 1231-5 (2005)
2009 8	Biological responses to arsenic compounds. [19363033] J Biol Chem 284(28): 18583-7 (2009)
2002 9	Molecular targets of arsenic trioxide in malignant cells. [11961205] Oncologist 7 Suppl 1(-): 14-9 (2002)
2003 10	Melanoma differentiation associated gene-7, mda-7/interleukin-24, induces apoptosis in prostate cancer cells by promoting mitochondrial dysfunction and inducing reactive oxygen species. [14678967] Cancer Res 63(23): 8138-44 (2003)
2011 11	A serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ROS and ceramide levels. [21119025] Mol Pharmacol 79(3): 368-80 (2011)
2006 12	Coordination of intrinsic, extrinsic, and endoplasmic reticulum-mediated apoptosis by imatinib mesylate combined with arsenic trioxide in chronic myeloid leukemia. [16249384] Blood 107(4): 1582-90 (2006)
2010 13	Arsenic trioxide - An old drug rediscovered. [20471733] Blood Rev 24(4-5): 191-9 (2010)
2002 14	Backing into cancer: effects of arsenic on cell differentiation. [11812918] Toxicol Sci 65(2): 161-3 (2002)

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