BRAF

LE WE PMID CA

BRAF

8055

BRAF

BRAF

Cardio facio cutaneous syndrome

Colon and rectum (Neoplasia)

ERK

PI3KC3

PLX4032

Skin (Neoplasia Melanoma)

Thyroid (Neoplasia)

Thyroid (Neoplasm Papillary thyroid carcinoma)

2009 1	Tumour cell survival signalling by the ERK1/2 pathway. [18846109] Cell Death Differ 16(3): 368-77 (2009)
2010 2	Selectively targeting mutant BRAF in thyroid cancer. [20056810] J Clin Endocrinol Metab 95(1): 60-1 (2010)
2010 3	BRAF, a target in melanoma: implications for solid tumor drug development. [20629085] Cancer 116(21): 4902-13 (2010)
2007 4	Clinicopathologic significance of BRAF V600E mutation in papillary carcinomas of the thyroid: a meta-analysis. [17520704] Cancer 110(1): 38-46 (2007)
2007 5	Targeting BRAF in thyroid cancer. [17179987] Br J Cancer 96(1): 16-20 (2007)
2009 6	Integrating BRAF/MEK inhibitors into combination therapy for melanoma. [19156138] Br J Cancer 100(3): 431-5 (2009)
2007 7	Clinical prognosis in BRAF-mutated PTC. [17891237] Arq Bras Endocrinol Metabol 51(5): 736-47 (2007)
2011 8	Potential therapeutic strategies to overcome acquired resistance to BRAF or MEK inhibitors in BRAF mutant cancers. [21505228] Oncotarget 2(4): 336-46 (2011)
2009 9	Spectrum of MEK1 and MEK2 gene mutations in cardio-facio-cutaneous syndrome and genotype-phenotype correlations. [19156172] Eur J Hum Genet 17(6): 733-40 (2009)
2010 10	Understanding melanoma signaling networks as the basis for molecular targeted therapy. [19571822] J Invest Dermatol 130(1): 28-37 (2010)
2010 11	Colorectal cancer: cetuximab, KRAS, BRAF, PIK3CA mutations and beyond. [20932136] Expert Rev Gastroenterol Hepatol 4(5): 525-9 (2010)
2010 12	Incidence of the V600K mutation among melanoma patients with BRAF mutations, and potential therapeutic response to the specific BRAF inhibitor PLX4032. [20630094] J Transl Med 8(-): 67 (2010)
2007 13	Mouse models for BRAF-induced cancers. [17956344] Biochem Soc Trans 35(Pt 5): 1329-33 (2007)
2011 14	Targeting BRAF for patients with melanoma. [21139585] Br J Cancer 104(3): 392-8 (2011)

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All Medline data shown were primarily retrieved from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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