ERS UFR (Pharmacology)

A dibenzoylmethane derivative protects dopaminergic neurons against both oxidative stress and endoplasmic reticulum stress.
[17913843] Am J Physiol Cell Physiol 293(6): C1884-94 (2007)

Inhibition of hepatic Niemann-Pick C1-like 1 improves hepatic insulin resistance.
[19654286] Am J Physiol Endocrinol Metab 297(5): E1030-8 (2009)

Cyclosporine triggers endoplasmic reticulum stress in endothelial cells: a role for endothelial phenotypic changes and death.
[18987109] Am J Physiol Renal Physiol 296(1): F160-9 (2009)

Coupling endoplasmic reticulum stress to the cell death program in mouse melanoma cells: effect of curcumin.
[18493855] Apoptosis 13(7): 904-14 (2008)

TRB3 links ER stress to autophagy in cannabinoid anti-tumoral action.
[19652543] Autophagy 5(7): 1048-9 (2009)

Nelfinavir, a new anti-cancer drug with pleiotropic effects and many paths to autophagy.
[18000394] Autophagy 4(1): 107-9 (2008)

Protective effects of 4-phenylbutyrate derivatives on the neuronal cell death and endoplasmic reticulum stress.
[22223342] Biol Pharm Bull 35(1): 84-90 (2012)

Efficacy of dibenzoylmethane derivatives in protecting against endoplasmic reticulum stress and inhibiting nuclear factor kappa B on dextran sulfate sodium induced colitis in mice.
[21139246] Biol Pharm Bull 33(12): 2029-32 (2010)

Targeting PKC: a novel role for beta-catenin in ER stress and apoptotic signaling.
[19018094] Blood 113(7): 1513-21 (2009)

Coordination of intrinsic, extrinsic, and endoplasmic reticulum-mediated apoptosis by imatinib mesylate combined with arsenic trioxide in chronic myeloid leukemia.
[16249384] Blood 107(4): 1582-90 (2006)

Tetrocarcin-A--induced ER stress mediates apoptosis in B-CLL cells via a Bcl-2--independent pathway.
[12560233] Blood 101(11): 4561-8 (2003)

Amiloride derivatives induce apoptosis by depleting ER Ca(2+) stores in vascular endothelial cells.
[19302589] Br J Pharmacol 156(8): 1296-304 (2009)

Piling up the JNK: drug synergy through ER stress.
[19458484] Cancer Biol Ther 8(9): 820-2 (2009)

Photodynamic therapy with 9-hydroxypheophorbide alpha on AMC-HN-3 human head and neck cancer cells: induction of apoptosis via photoactivation of mitochondria and endoplasmic reticulum.
[19421004] Cancer Biol Ther 8(14): 1343-51 (2009)

Inhibition of RNA-dependent protein kinase (PKR) leads to cancer cell death and increases chemosensitivity.
[19106640] Cancer Biol Ther 8(3): 245-52 (2009)

Enhancement of photodynamic therapy by 2,5-dimethyl celecoxib, a non-cyclooxygenase-2 inhibitor analog of celecoxib.
[21339042] Cancer Lett 304(1): 33-40 (2011)

Inhibition of autophagy enhances anticancer effects of atorvastatin in digestive malignancies.
[20876807] Cancer Res 70(19): 7699-709 (2010)

Increasing melanoma cell death using inhibitors of protein disulfide isomerases to abrogate survival responses to endoplasmic reticulum stress.
[18593938] Cancer Res 68(13): 5363-9 (2008)

Targeting endoplasmic reticulum stress and Akt with OSU-03012 and gefitinib or erlotinib to overcome resistance to epidermal growth factor receptor inhibitors.
[18413750] Cancer Res 68(8): 2820-30 (2008)

The unhydrolyzable fenretinide analogue 4-hydroxybenzylretinone induces the proapoptotic genes GADD153 (CHOP) and Bcl-2-binding component 3 (PUMA) and apoptosis that is caspase- dependent and independent of the retinoic acid receptor.
[17616685] Cancer Res 67(13): 6270-7 (2007)

PLAB induction in fenretinide-induced apoptosis of ovarian cancer cells occurs via a ROS-dependent mechanism involving ER stress and JNK activation.
[19325135] Carcinogenesis 30(5): 824-31 (2009)

Role of Smac in cephalostatin-induced cell death.
[18806754] Cell Death Differ 15(12): 1930-40 (2008)

z-VAD-fmk inhibits peptide:N-glycanase and may result in ER stress.
[16003388] Cell Death Differ 13(1): 163-5 (2006)

Beyond reduction of atherosclerosis: PON2 provides apoptosis resistance and stabilizes tumor cells.
[21368884] Cell Death Dis 2(): e112 (2011)

Calcineurin is involved in cardioprotection induced by ischemic postconditioning through attenuating endoplasmic reticulum stress.
[22088531] Chin Med J (Engl) 124(20): 3334-40 (2011)

Inducible expression of active protein phosphatase-1 inhibitor-1 enhances basal cardiac function and protects against ischemia/reperfusion injury.
[19299645] Circ Res 104(8): 1012-20 (2009)

1,25(OH)2 vitamin d inhibits foam cell formation and suppresses macrophage cholesterol uptake in patients with type 2 diabetes mellitus.
[19667238] Circulation 120(8): 687-98 (2009)

Histone deacetylase inhibitors and 15-deoxy-Delta12,14-prostaglandin J2 synergistically induce apoptosis.
[20371690] Clin Cancer Res 16(8): 2320-32 (2010)

The combined therapeutic effects of bortezomib and fenretinide on neuroblastoma cells involve endoplasmic reticulum stress response.
[19228726] Clin Cancer Res 15(4): 1199-209 (2009)

Combining the endoplasmic reticulum stress-inducing agents bortezomib and fenretinide as a novel therapeutic strategy for metastatic melanoma.
[19228725] Clin Cancer Res 15(4): 1192-8 (2009)

Nelfinavir, A lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo.
[17785575] Clin Cancer Res 13(17): 5183-94 (2007)

Ursodeoxycholic acid in cholestasis: linking action mechanisms to therapeutic applications.
[21854363] Clin Sci (Lond) 121(12): 523-44 (2011)

Gene-activation mechanisms in the regression of atherosclerosis, elimination of diabetes type 2, and prevention of dementia.
[21568932] Curr Mol Med 11(5): 391-400 (2011)

Stressed to death: targeting endoplasmic reticulum stress response induced apoptosis in gliomas.
[21348829] Curr Pharm Des 17(3): 284-92 (2011)

Sodium phenylbutyrate, a drug with known capacity to reduce endoplasmic reticulum stress, partially alleviates lipid-induced insulin resistance and beta-cell dysfunction in humans.
[21270237] Diabetes 60(3): 918-24 (2011)

Activation of AMP-activated protein kinase inhibits oxidized LDL-triggered endoplasmic reticulum stress in vivo.
[20299472] Diabetes 59(6): 1386-96 (2010)

Therapeutic potential of peroxisome proliferators--activated receptor-alpha/gamma dual agonist with alleviation of endoplasmic reticulum stress for the treatment of diabetes.
[18065517] Diabetes 57(3): 737-45 (2008)

The human glucagon-like peptide-1 analogue liraglutide preserves pancreatic beta cells via regulation of cell kinetics and suppression of oxidative and endoplasmic reticulum stress in a mouse model of diabetes.
[21340625] Diabetologia 54(5): 1098-108 (2011)

Oleate blocks palmitate-induced abnormal lipid distribution, endoplasmic reticulum expansion and stress, and insulin resistance in skeletal muscle.
[21505048] Endocrinology 152(6): 2206-18 (2011)

Widespread cortical expression of MANF by AAV serotype 7: localization and protection against ischemic brain injury.
[20685313] Exp Neurol 225(1): 104-13 (2010)

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