Eicosanoid

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Eicosanoid

LE WE PMID CA

Eicosanoid

761

Eicosanoid

4 Hydroxynonenal

Eicosanoid

Methods of biochemical experimentation

Ramatroban

1987 1	The arachidonic acid cascade: an immunologically based review. [2828503] J Med 18(2): 69-80 (1987)
2004 2	Ramatroban (BAY u 3405): a novel dual antagonist of TXA2 receptor and CRTh2, a newly identified prostaglandin D2 receptor. [15179446] Cardiovasc Drug Rev 22(2): 71-90 (2004)
1996 3	Physiological and pathophysiological roles of eicosanoids in the microcirculation. [8915190] Cardiovasc Res 32(4): 720-32 (1996)
2007 4	Membrane prostaglandin E synthase-1: a novel therapeutic target. [17878511] Pharmacol Rev 59(3): 207-24 (2007)
2006 5	Eicosanoid transcellular biosynthesis: from cell-cell interactions to in vivo tissue responses. [16968946] Pharmacol Rev 58(3): 375-88 (2006)
2005 6	Modulation of prostaglandin biosynthesis by nitric oxide and nitric oxide donors. [15914468] Pharmacol Rev 57(2): 217-52 (2005)
2008 7	Cytochrome P-450 metabolites in renal circulation and excretion--interaction with the nitric oxide (NO) system. [19261977] J Physiol Pharmacol 59 Suppl 9(-): 137-49 (2008)
2000 8	Trans-arachidonic acids: new mediators of inflammation. [11192934] J Physiol Pharmacol 51(4 Pt 1): 597-607 (2000)
2003 9	Production of eicosanoids and other oxylipins by pathogenic eukaryotic microbes. [12857780] Clin Microbiol Rev 16(3): 517-33 (2003)
1992 10	Roles of renal cytochrome P450-dependent arachidonic acid metabolites in hypertension. [1412450] Tohoku J Exp Med 166(1): 93-106 (1992)
2003 11	Evaluation of the whole prostaglandin biosynthetic pathway in lung cancer. [12738708] Clin Cancer Res 9(5): 1577-8 (2003)
2002 12	P-450 metabolites of arachidonic acid in the control of cardiovascular function. [11773611] Physiol Rev 82(1): 131-85 (2002)
1999 13	Prostanoid receptors: structures, properties, and functions. [10508233] Physiol Rev 79(4): 1193-226 (1999)
1992 14	Cytochrome P450 and the arachidonate cascade. [1537463] FASEB J 6(2): 731-6 (1992)
2007 15	Control of oxygenation in lipoxygenase and cyclooxygenase catalysis. [17524979] Chem Biol 14(5): 473-88 (2007)
2004 16	The cyclooxygenases. [15345041] Genome Biol 5(9): 241 (2004)
2005 17	Prostaglandin E synthase, a terminal enzyme for prostaglandin E2 biosynthesis. [16336776] J Biochem Mol Biol 38(6): 633-8 (2005)
2008 18	Human biochemistry of the isoprostane pathway. [18285331] J Biol Chem 283(23): 15533-7 (2008)
2007 19	Prostaglandin E receptors. [17329241] J Biol Chem 282(16): 11613-7 (2007)
2004 20	Leukotriene A4 hydrolase/aminopeptidase, the gatekeeper of chemotactic leukotriene B4 biosynthesis. [15339917] J Biol Chem 279(49): 50639-42 (2004)
2001 21	Epoxygenase pathways of arachidonic acid metabolism. [11451964] J Biol Chem 276(39): 36059-62 (2001)
1999 22	Isoprostanes: formation, analysis and use as indices of lipid peroxidation in vivo. [10455102] J Biol Chem 274(35): 24441-4 (1999)
1999 23	Lipoxygenases: occurrence, functions, catalysis, and acquisition of substrate. [10446122] J Biol Chem 274(34): 23679-82 (1999)
1999 24	Arachidonic acid oxygenation by COX-1 and COX-2. Mechanisms of catalysis and inhibition. [10438452] J Biol Chem 274(33): 22903-6 (1999)
1996 25	Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2. [8969167] J Biol Chem 271(52): 33157-60 (1996)
1989 26	Enzymes involved in the biosynthesis of leukotriene B4. [2555321] J Biol Chem 264(33): 19469-72 (1989)
1998 27	Radically novel prostaglandins in animals and plants: the isoprostanes. [9862802] Chem Biol 5(12): R323-33 (1998)
1997 28	New insights from spectroscopy into the structure/function relationships of lipoxygenases. [9384534] Chem Biol 4(11): 795-808 (1997)
1999 29	Cyclooxygenase-dependent signalling: molecular events and consequences. [10069362] FEBS Lett 445(1): 1-5 (1999)
1998 30	Cellular regulation of prostaglandin H synthase catalysis. [9688529] FEBS Lett 430(3): 154-7 (1998)
1994 31	Prostaglandin H synthase: implications for membrane structure. [8206152] FEBS Lett 346(1): 21-5 (1994)
1980 32	The prostanoids in hemostasis and thrombosis: a review. [6992594] Am J Pathol 99(3): 743-804 (1980)
2007 33	Action of epoxyeicosatrienoic acids on cellular function. [16987999] Am J Physiol Cell Physiol 292(3): C996-1012 (2007)
2001 34	The lung HETEs (and EETs) up. [11123211] Am J Physiol Heart Circ Physiol 280(1): H1-H10 (2001)
2004 35	Leukocyte inflammatory mediators and lung pathophysiology: an update. [14761869] Am J Physiol Lung Cell Mol Physiol 286(3): L461-2 (2004)
2004 36	Protection against proximal tubule necrosis with 11-deoxy-16,16-dimethyl prostaglandin E2 in vitro. [15522989] Am J Physiol Renal Physiol 287(6): F1111-2 (2004)
2000 37	Intracellular compartmentalization of leukotriene biosynthesis. [10673224] Am J Respir Crit Care Med 161(2 Pt 2): S36-40 (2000)
2000 38	Membrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG). A widespread protein superfamily. [10673221] Am J Respir Crit Care Med 161(2 Pt 2): S20-4 (2000)
2000 39	The discovery of the leukotrienes. [10673217] Am J Respir Crit Care Med 161(2 Pt 2): S2-6 (2000)
2007 40	Epoxyeicosatrienoic acids, TRP channels, and intracellular Ca2+ in the vasculature: an endothelium-derived endothelium-hyperpolarizing factor? [17962695] Arterioscler Thromb Vasc Biol 27(12): 2496-8 (2007)
1989 41	The eicosanoids and their biochemical mechanisms of action. [2655580] Biochem J 259(2): 315-24 (1989)
1989 42	Metabolic interactions between eicosanoids in blood and vascular cells. [2494983] Biochem J 257(2): 313-20 (1989)
2005 43	Cysteinyl leukotrienes in allergic inflammation: strategic target for therapy. [15821210] Chest 127(4): 1312-26 (2005)
2001 44	Prostaglandin H synthase and vascular function. [11597987] Circ Res 89(8): 650-60 (2001)
1999 45	Endothelium-derived hyperpolarizing factors and vascular cytochrome P450 metabolites of arachidonic acid in the regulation of tone. [10066684] Circ Res 84(4): 484-8 (1999)
2007 46	Cardiovascular effects of the cyclooxygenase inhibitors. [17261646] Hypertension 49(3): 408-18 (2007)
2007 47	Arachidonic acid metabolites as endothelium-derived hyperpolarizing factors. [17200437] Hypertension 49(3): 590-6 (2007)
2006 48	Endothelium-derived epoxyeicosatrienoic acids and vascular function. [16490839] Hypertension 47(4): 629-33 (2006)
2001 49	Unorthodox routes to prostanoid formation: new twists in cyclooxygenase-initiated pathways. [11413151] J Clin Invest 107(12): 1481-9 (2001)
2001 50	Regulated formation of eicosanoids. [11390414] J Clin Invest 107(11): 1347-51 (2001)
2001 51	Arachidonic acid as a bioactive molecule. [11390413] J Clin Invest 107(11): 1339-45 (2001)
1984 52	The biologically active leukotrienes. Biosynthesis, metabolism, receptors, functions, and pharmacology. [6323538] J Clin Invest 73(4): 889-97 (1984)
2001 53	Sources of eicosanoid precursor fatty acid pools in tissues. [11590208] J Lipid Res 42(10): 1521-42 (2001)
2000 54	Cytochrome P450 and arachidonic acid bioactivation. Molecular and functional properties of the arachidonate monooxygenase. [10681399] J Lipid Res 41(2): 163-81 (2000)
2001 55	Cytochrome P450 metabolites of arachidonic acid: novel regulators of renal function. [11733614] Nephrol Dial Transplant 16(12): 2283-5 (2001)
1998 56	Leukotrienes and lipoxins: lipoxygenase-derived modulators of leukocyte recruitment and vascular tone in glomerulonephritis. [9870464] Nephrol Dial Transplant 13(12): 3043-51 (1998)
2000 57	A new class of lipid mediators: cytochrome P450 arachidonate metabolites. [10992547] Thorax 55 Suppl 2(-): S13-6 (2000)
1985 58	Navigating the sea of eicosanoids. [3004045] West J Med 143(4): 516-7 (1985)
1985 59	Prostaglandins, thromboxanes and leukotrienes in clinical medicine. [3004043] West J Med 143(4): 485-97 (1985)
2003 60	Identification of an endogenous inhibitor of arachidonate metabolism in human epidermoid carcinoma A431 cells. [14576462] J Biomed Sci 10(6 Pt 1): 599-606 (2003)
2009 61	Eicosanoid signalling pathways in the heart. [19074824] Cardiovasc Res 82(2): 240-9 (2009)
2009 62	Prostanoids in health and disease. [19095631] J Lipid Res 50 Suppl(-): S423-8 (2009)
2009 63	Prostanoid receptor antagonists: development strategies and therapeutic applications. [19624532] Br J Pharmacol 158(1): 104-45 (2009)
2003 64	The organization and consequences of eicosanoid signaling. [12697726] J Clin Invest 111(8): 1107-13 (2003)
2010 65	Transcellular biosynthesis of eicosanoids. [20631414] Pharmacol Rep 62(3): 503-10 (2010)
2009 66	Targeted quantitative analysis of eicosanoid lipids in biological samples using liquid chromatography-tandem mass spectrometry. [19345647] J Chromatogr B Analyt Technol Biomed Life Sci 877(26): 2736-45 (2009)
2010 67	Signaling and cytotoxic functions of 4-hydroxyalkenals. [20858748] Am J Physiol Endocrinol Metab 299(6): E879-86 (2010)

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