Fibrosis

Fibrosis regression induced by intravenous gammaglobulin treatment.
[12525390] Ann Rheum Dis 62(2): 175-7 (2003)

Transforming growth factor-beta signal transduction and progressive renal disease.
[12486204] Exp Biol Med (Maywood) 227(11): 943-56 (2002)

Molecular ablation of transforming growth factor beta signaling pathways by tyrosine kinase inhibition: the coming of a promising new era in the treatment of tissue fibrosis.
[18668575] Arthritis Rheum 58(8): 2219-24 (2008)

Hypoxia-inducible factor signaling in the development of tissue fibrosis.
[18418042] Cell Cycle 7(9): 1128-32 (2008)

Gene expression in fibroblasts and fibrosis: involvement in cardiac hypertrophy.
[12480810] Circ Res 91(12): 1103-13 (2002)

Peroxisome proliferator-activated receptor gamma agonists in renal disease.
[16645006] Eur J Endocrinol 154(5): 613-21 (2006)

Fibrosis and diseases of the eye.
[17332885] J Clin Invest 117(3): 576-86 (2007)

Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organ.
[17332881] J Clin Invest 117(3): 539-48 (2007)

Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases.
[17332879] J Clin Invest 117(3): 524-9 (2007)

Pulmonary fibrosis: thinking outside of the lung.
[15286797] J Clin Invest 114(3): 319-21 (2004)

Matrix metalloproteinases and their inhibitors as markers of inflammation and fibrosis in chronic liver disease (Review).
[19578787] Int J Mol Med 24(2): 143-52 (2009)

The controversial role of tumor necrosis factor alpha in fibrotic diseases.
[18668576] Arthritis Rheum 58(8): 2228-35 (2008)

Stimulatory autoantibodies to platelet-derived growth factor receptors in systemic sclerosis: what functional autoimmunity could learn from receptor biology.
[19333918] Arthritis Rheum 60(4): 907-11 (2009)

Wnt signaling and pulmonary fibrosis.
[12707021] Am J Pathol 162(5): 1393-7 (2003)

Emerging concepts in the pathogenesis of lung fibrosis.
[19497999] Am J Pathol 175(1): 3-16 (2009)

A murine model of alcoholic cardiomyopathy: a role for zinc and metallothionein in fibrosis.
[16049317] Am J Pathol 167(2): 301-4 (2005)

Integrin-mediated transforming growth factor-beta activation, a potential therapeutic target in fibrogenic disorders.
[19729474] Am J Pathol 175(4): 1362-70 (2009)

Endocannabinoids and liver disease. II. Endocannabinoids in the pathogenesis and treatment of liver fibrosis.
[18006606] Am J Physiol Gastrointest Liver Physiol 294(2): G357-62 (2008)

Role of lysyl oxidase in myocardial fibrosis: from basic science to clinical aspects.
[20472764] Am J Physiol Heart Circ Physiol 299(1): H1-9 (2010)

Could N-acetylcysteine slow progression of idiopathic pulmonary fibrosis by inhibiting EMT?
[19700642] Am J Physiol Lung Cell Mol Physiol 297(5): L803-4 (2009)

Caveolin-1 stops profibrogenic signaling?
[18296500] Am J Physiol Lung Cell Mol Physiol 294(5): L841-2 (2008)

Antifibrotic properties of caveolin-1 scaffolding domain in vitro and in vivo.
[18203815] Am J Physiol Lung Cell Mol Physiol 294(5): L843-61 (2008)

Lysophosphatidic acid and renal fibrosis.
[18455518] Biochim Biophys Acta 1781(9): 582-7 (2008)

Signaling pathways in the epithelial origins of pulmonary fibrosis.
[20676040] Cell Cycle 9(14): 2769-76 (2010)

Reactivation of Snail genes in renal fibrosis and carcinomas: a process of reversed embryogenesis?
[17374993] Cell Cycle 6(6): 638-42 (2007)

Targeting collagen expression in alcoholic liver disease.
[21633652] World J Gastroenterol 17(20): 2473-81 (2011)

Transforming growth factor-beta and fibrosis.
[17589920] World J Gastroenterol 13(22): 3056-62 (2007)

Role of iron in hepatic fibrosis: one piece in the puzzle.
[17729396] World J Gastroenterol 13(35): 4746-54 (2007)

Renin-angiotensin system in the pathogenesis of liver fibrosis.
[19496186] World J Gastroenterol 15(21): 2579-86 (2009)

Syndecan-1: a critical mediator in cardiac fibrosis.
[20048190] Hypertension 55(2): 233-5 (2010)

Are peroxisome proliferator-activated receptors new therapeutic targets in diabetic and non-diabetic nephropathies?
[16880183] Nephrol Dial Transplant 21(10): 2696-702 (2006)

Renal fibrosis and the origin of the renal fibroblast.
[16887850] Nephrol Dial Transplant 21(12): 3368-70 (2006)

The thrombospondin 1-TGF-beta axis in fibrotic renal disease.
[12808154] Nephrol Dial Transplant 18(7): 1241-5 (2003)

Molecular targets in pulmonary fibrosis: the myofibroblast in focus.
[17934117] Chest 132(4): 1311-21 (2007)

Potential therapeutic targets for cardiac fibrosis: TGFbeta, angiotensin, endothelin, CCN2, and PDGF, partners in fibroblast activation.
[20538689] Circ Res 106(11): 1675-80 (2010)

Protein acetylation in the cardiorenal axis: the promise of histone deacetylase inhibitors.
[20133912] Circ Res 106(2): 272-84 (2010)

"Obese" smooth muscle cells fail to assemble collagen fibrils.
[19359604] Circ Res 104(7): 826-8 (2009)

A transgenic mouse model for studying the role of the parathyroid hormone-related protein system in renal injury.
[21052497] J Biomed Biotechnol 2011(-): 290874 (2011)

TGFbeta, cardiac fibroblasts, and the fibrotic response.
[16919613] Cardiovasc Res 74(2): 207-12 (2007)

TGF-beta signaling in vascular fibrosis.
[17376414] Cardiovasc Res 74(2): 196-206 (2007)

Fibrogenesis of parenchymal organs.
[18403330] Proc Am Thorac Soc 5(3): 338-42 (2008)

What differentiates normal lung repair and fibrosis? Inflammation, resolution of repair, and fibrosis.
[18403324] Proc Am Thorac Soc 5(3): 305-10 (2008)

Epithelial origin of myofibroblasts during fibrosis in the lung.
[16738204] Proc Am Thorac Soc 3(4): 377-82 (2006)

Transgenic modeling of transforming growth factor-beta(1): role of apoptosis in fibrosis and alveolar remodeling.
[16799085] Proc Am Thorac Soc 3(5): 418-23 (2006)

Transforming growth factor beta: a central modulator of pulmonary and airway inflammation and fibrosis.
[16799084] Proc Am Thorac Soc 3(5): 413-7 (2006)

Reversal of renal disease: is it enough to inhibit the action of angiotensin II?
[17396129] Cell Death Differ 14(7): 1343-9 (2007)

Therapeutic potential of follistatin to promote tissue regeneration and prevent tissue fibrosis.
[17938504] Endocr J 54(6): 849-54 (2007)

New approaches to blockade of the renin-angiotensin-aldosterone system: chymase as an important target to prevent organ damage.
[20675958] J Pharmacol Sci 113(4): 301-9 (2010)

Drug discovery for overcoming chronic kidney disease (CKD): new therapy for CKD by a (pro)renin-receptor-blocking decoy peptide.
[19151536] J Pharmacol Sci 109(1): 20-3 (2009)

Fibrocytes: bringing new insights into mechanisms of inflammation and fibrosis.
[19850147] Int J Biochem Cell Biol 42(4): 535-42 (2010)

Imatinib as a novel therapeutic approach for fibrotic disorders.
[19029132] Rheumatology (Oxford) 48(1): 2-4 (2009)

Role of PDGF in fibrotic diseases and systemic sclerosis.
[18784131] Rheumatology (Oxford) 47 Suppl 5(-): v2-4 (2008)

Criteria to select molecular targets for anti-fibrotic therapy.
[18784127] Rheumatology (Oxford) 47 Suppl 5(-): v12-3 (2008)

Intracellular tyrosine kinases as novel targets for anti-fibrotic therapy in systemic sclerosis.
[18784126] Rheumatology (Oxford) 47 Suppl 5(-): v10-1 (2008)

Extracellular superoxide dismutase in pulmonary fibrosis.
[17999630] Antioxid Redox Signal 10(2): 343-54 (2008)

Antioxidants as potential therapeutics for lung fibrosis.
[17999627] Antioxid Redox Signal 10(2): 355-70 (2008)

The role of inflammation in the pathogenesis of idiopathic pulmonary fibrosis.
[17961066] Antioxid Redox Signal 10(2): 287-301 (2008)

Resolving the scar of pulmonary fibrosis.
[21992127] N Engl J Med 365(12): 1140-1 (2011)

Regression of liver fibrosis in patients treated by interferon.
[15575231] Intern Med 43(10): 887-8 (2004)

Rationale and targets for antifibrotic therapies.
[19726145] Gastroenterol Clin Biol 33(10-11): 949-57 (2009)

IL-6 and extracellular matrix remodeling.
[16266225] Rev Esp Enferm Dig 97(8): 575-95 (2005)

Hepatocyte growth factor in kidney fibrosis: therapeutic potential and mechanisms of action.
[15180923] Am J Physiol Renal Physiol 287(1): F7-16 (2004)

TGF-beta signal transduction and mesangial cell fibrogenesis.
[12529270] Am J Physiol Renal Physiol 284(2): F243-52 (2003)

Fibrotic disease and the T(H)1/T(H)2 paradigm.
[15286725] Nat Rev Immunol 4(8): 583-94 (2004)

Epithelial injury induces an innate repair mechanism linked to cellular senescence and fibrosis involving IGF-binding protein-5.
[18676497] J Endocrinol 199(2): 155-64 (2008)

Melatonin ameliorates experimental hepatic fibrosis induced by carbon tetrachloride in rats.
[19322917] World J Gastroenterol 15(12): 1452-8 (2009)

Deficiency of rac1 blocks NADPH oxidase activation, inhibits endoplasmic reticulum stress, and reduces myocardial remodeling in a mouse model of type 1 diabetes.
[20522592] Diabetes 59(8): 2033-42 (2010)

MicroRNAs and the regulation of fibrosis.
[20412055] FEBS J 277(9): 2015-21 (2010)

Oxidative stress and glutathione in TGF-beta-mediated fibrogenesis.
[19800967] Free Radic Biol Med 48(1): 1-15 (2010)

Protective effect of TRPV1 against renal fibrosis via inhibition of TGF-beta/Smad signaling in DOCA-salt hypertension.
[21792478] Mol Med 17(11-12): 1204-12 (2011)

Molecular pathogenesis of skin fibrosis: insight from animal models.
[20425530] Curr Rheumatol Rep 12(1): 26-33 (2010)

Innovative approaches to the therapy of fibrosis.
[19667993] Curr Opin Rheumatol 21(6): 649-55 (2009)

Oxidative and nitrosative stress and fibrogenic response.
[18984466] Clin Liver Dis 12(4): 769-90, viii (2008)

Cellular and molecular mechanisms of fibrosis.
[18161745] J Pathol 214(2): 199-210 (2008)

Macrophages: master regulators of inflammation and fibrosis.
[20665377] Semin Liver Dis 30(3): 245-57 (2010)

Scraping fibrosis: expressway to the core of fibrosis.
[21546973] Nat Med 17(5): 552-3 (2011)

Fibrosis and cancer: do myofibroblasts come also from epithelial cells via EMT?
[17211838] J Cell Biochem 101(4): 830-9 (2007)

Overview about the keloid scars and the elaboration of a non-invasive, unconventional treatment.
[20968196] J Med Life 3(2): 122-7 (2010)

The origin of fibroblasts and mechanism of cardiac fibrosis.
[20635395] J Cell Physiol 225(3): 631-7 (2010)

Cellular and molecular mechanisms underlying bone marrow and liver fibrosis: a review.
[18632420] Eur Cytokine Netw 19(2): 69-80 (2008)

Relaxin and its role in the development and treatment of fibrosis.
[19524867] Transl Res 154(1): 1-6 (2009)

Adenosine receptors and fibrosis: a translational review.
[22003368] F1000 Biol Rep 3(-): 21 (2011)

Fibrosis: recent advances in myofibroblast biology and new therapeutic perspectives.
[21170369] F1000 Biol Rep 2(-): 78 (2010)

Vitamin D inhibition of TACE and prevention of renal osteodystrophy and cardiovascular mortality.
[20359533] J Steroid Biochem Mol Biol 121(1-2): 193-8 (2010)

Immune mechanisms in thyroid eye disease.
[18752427] Thyroid 18(9): 959-65 (2008)

The role of fibrocytes in fibrotic diseases of the lungs and heart.
[21219601] Fibrogenesis Tissue Repair 4(-): 2 (2011)

Role of host genetics in fibrosis.
[19961576] Fibrogenesis Tissue Repair 2(1): 6 (2009)

Focus on collagen: in vitro systems to study fibrogenesis and antifibrosis state of the art.
[20003476] Fibrogenesis Tissue Repair 2(-): 7 (2009)

Redox mechanisms in hepatic chronic wound healing and fibrogenesis.
[19014652] Fibrogenesis Tissue Repair 1(1): 5 (2008)

Mechanoregulation of gene expression in fibroblasts.
[17331678] Gene 391(1-2): 1-15 (2007)

Navigating the challenges of fibrosis assessment: land in sight?
[21127139] J Am Soc Nephrol 22(1): 11-3 (2011)

Topical endotracheal mitomycin C as a complementary treatment for endoscopic treatment of recurrent laryngotracheal stenosis.
[20663704] Farm Hosp 35(1): 32-5 (2011)

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