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G Protein coupled receptor
LE WE PMID CA
G Protein coupled receptor4089G Protein verbundener Rezeptor

Allosteric modulation

ALX0651 ttCXCR4

Antibodies (therapeutic use)

beta Arrestin

Dynamin

G Protein coupled receptor

GASP1

Genetics (Imprinting)

GNAS

Heart failure (chronical)

KW0761 AMG761 ttCCR4

McCune Albright syndrome

MDX1338 ttCXCR4

MLN1201 ttCCR2

MLN1202 ttCCR2

NADPH oxidase

PRO140 ttCCR5

Protein (protein binding)

PTH (Pseudohypoparathyroidism)

R7BP

R9AP

RAMP1

RAMP2

RAMP3

Receptor (activity modifying proteins)

Receptor (Endocytosis)

Receptor (Intracellular transport)

Receptor (Neoceptor Neoligand)

Receptor (Transactivation)

Redox (Signal transduction)

RGS protein family

RGS11

RGS2

RGS6

RGS7

RGS9

Rhodopsin

RhoGEF

S nitrosothiol

Spinophilin

TRPV6

2008  
1
G-protein-coupled receptor phosphorylation: where, when and by whom.
[18193069] Br J Pharmacol 153 Suppl 1(-): S167-76 (2008)
2008  
2
Agonist-selective mechanisms of GPCR desensitization.
[18059321] Br J Pharmacol 153 Suppl 1(-): S379-88 (2008)
2008  
3
Conformational changes in G-protein-coupled receptors-the quest for functionally selective conformations is open.
[18059316] Br J Pharmacol 153 Suppl 1(-): S358-66 (2008)
2008  
4
A day in the life of a G protein-coupled receptor: the contribution to function of G protein-coupled receptor dimerization.
[17965750] Br J Pharmacol 153 Suppl 1(-): S216-29 (2008)
2006  
5
G-protein-coupled receptors: past, present and future.
[16402114] Br J Pharmacol 147 Suppl 1(-): S27-37 (2006)
2007  
6
G protein-coupled receptor trafficking in health and disease: lessons learned to prepare for therapeutic mutant rescue in vivo.
[17878512] Pharmacol Rev 59(3): 225-50 (2007)
2005  
7
Heterodimerization of g protein-coupled receptors: specificity and functional significance.
[16109836] Pharmacol Rev 57(3): 289-98 (2005)
2005  
8
International Union of Pharmacology. XLVI. G protein-coupled receptor list.
[15914470] Pharmacol Rev 57(2): 279-88 (2005)
2005  
9
Multiple signaling states of G-protein-coupled receptors.
[15914464] Pharmacol Rev 57(2): 147-61 (2005)
2004  
10
Single transmembrane spanning heterotrimeric g protein-coupled receptors and their signaling cascades.
[15317909] Pharmacol Rev 56(3): 371-85 (2004)
2002  
11
G protein-coupled receptor allosterism and complexing.
[12037145] Pharmacol Rev 54(2): 323-74 (2002)
2002  
12
International Union of Pharmacology. XXXI. Recommendations for the nomenclature of multimeric G protein-coupled receptors.
[12037139] Pharmacol Rev 54(2): 231-2 (2002)
2001  
13
Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling.
[11171937] Pharmacol Rev 53(1): 1-24 (2001)
2007  
14
3-Dimensional structures of G protein-coupled receptors and binding sites of agonists and antagonists.
[17513420] J Nutr 137(6 Suppl 1): 1528S-1538S; discussion 1548S (2007)
2007  
15
Regulation of G protein-coupled receptor export trafficking.
[17074298] Biochim Biophys Acta 1768(4): 853-70 (2007)
2007  
16
G protein-coupled receptors in major psychiatric disorders.
[17078926] Biochim Biophys Acta 1768(4): 976-93 (2007)
2007  
17
Impact of GPCRs in clinical medicine: monogenic diseases, genetic variants and drug targets.
[17081496] Biochim Biophys Acta 1768(4): 994-1005 (2007)
2007  
18
G protein coupled receptor structure and activation.
[17188232] Biochim Biophys Acta 1768(4): 794-807 (2007)
2007  
19
Cardiac GPCRs: GPCR signaling in healthy and failing hearts.
[17376402] Biochim Biophys Acta 1768(4): 1006-18 (2007)
2010  
20
Energy landscapes as a tool to integrate GPCR structure, dynamics, and function.
[20940434] Physiology (Bethesda) 25(5): 293-303 (2010)
2007  
21
Visual rhodopsin sees the light: structure and mechanism of G protein signaling.
[17289671] J Biol Chem 282(13): 9297-301 (2007)
2011  
22
The paradigm of G protein receptor transactivation: a mechanistic definition and novel example.
[21442148] ScientificWorldJournal 11(-): 709-14 (2011)
2010  
23
Structure-function relationships of the N-terminus of receptor activity-modifying proteins.
[20015292] Br J Pharmacol 159(5): 1059-68 (2010)
2009  
24
G protein-coupled receptor hetero-dimerization: contribution to pharmacology and function.
[19309353] Br J Pharmacol 158(1): 5-14 (2009)
2009  
25
Regulation of RhoGEF proteins by G12/13-coupled receptors.
[19226283] Br J Pharmacol 158(1): 41-9 (2009)
2008  
26
2008  
27
G-protein-coupled receptor heteromers: function and ligand pharmacology.
[18037920] Br J Pharmacol 153 Suppl 1(-): S90-8 (2008)
2010  
28
The impact of GPCR structures on pharmacology and structure-based drug design.
[19912230] Br J Pharmacol 159(5): 986-96 (2010)
2008  
29
G protein betagamma subunits: central mediators of G protein-coupled receptor signaling.
[18488142] Cell Mol Life Sci 65(14): 2191-214 (2008)
2011  
30
Exploring a role for heteromerization in GPCR signalling specificity.
[21158738] Biochem J 433(1): 11-8 (2011)
2009  
31
Fine-tuning of GPCR activity by receptor-interacting proteins.
[19935667] Nat Rev Mol Cell Biol 10(12): 819-30 (2009)
2004  
32
Biochemistry of transmembrane signaling mediated by trimeric G proteins.
[15119945] Physiol Res 53 Suppl 1(-): S141-52 (2004)
2008  
33
Constitutive activation of G protein-coupled receptors and diseases: insights into mechanisms of activation and therapeutics.
[18768149] Pharmacol Ther 120(2): 129-48 (2008)
2010  
34
Chemical modification of class II G protein-coupled receptor ligands: frontiers in the development of peptide analogs as neuroendocrine pharmacological therapies.
[19686775] Pharmacol Ther 125(1): 39-54 (2010)
2007  
35
R4 RGS proteins: regulation of G-protein signaling and beyond.
[18006065] Pharmacol Ther 116(3): 473-95 (2007)
2009  
36
Physiological and pharmacological implications of beta-arrestin regulation.
[19100766] Pharmacol Ther 121(3): 285-93 (2009)
2006  
37
The structural basis of arrestin-mediated regulation of G-protein-coupled receptors.
[16460808] Pharmacol Ther 110(3): 465-502 (2006)
2004  
38
Minireview: Diversity and complexity of signaling through peptidergic G protein-coupled receptors.
[15044354] Endocrinology 145(6): 2645-52 (2004)
2004  
39
Minireview: GNAS: normal and abnormal functions.
[15331575] Endocrinology 145(12): 5459-64 (2004)
2010  
40
Oligomerization of G-protein-coupled receptors: a reality.
[20015687] Curr Opin Pharmacol 10(1): 1-5 (2010)
2009  
41
Vascular signaling through G protein-coupled receptors: new concepts.
[19434053] Curr Opin Nephrol Hypertens 18(2): 153-9 (2009)
2006  
42
RGS2 inhibits the epithelial Ca2+ channel TRPV6.
[16895908] J Biol Chem 281(40): 29669-74 (2006)
2004  
43
G protein-coupled receptor dimerization: function and ligand pharmacology.
[15213289] Mol Pharmacol 66(1): 1-7 (2004)
2004  
44
The ants go marching two by two: oligomeric structure of G-protein-coupled receptors.
[15319448] Mol Pharmacol 66(5): 1077-82 (2004)
2004  
45
Ca2+ channels as integrators of G protein-mediated signaling in neurons.
[15269290] Mol Pharmacol 66(5): 1071-6 (2004)
2007  
46
Receptor-mediated activation of heterotrimeric G-proteins: current structural insights.
[17430994] Mol Pharmacol 72(2): 219-30 (2007)
2005  
47
Internal PDZ ligands: novel endocytic recycling motifs for G protein-coupled receptors.
[15713849] Mol Pharmacol 67(5): 1388-90 (2005)
2009  
48
R9AP and R7BP: traffic cops for the RGS7 family in phototransduction and neuronal GPCR signaling.
[19042037] Trends Pharmacol Sci 30(1): 17-24 (2009)
2007  
49
Multiple GPCR conformations and signalling pathways: implications for antagonist affinity estimates.
[17629959] Trends Pharmacol Sci 28(8): 374-81 (2007)
2007  
50
GPCR functional selectivity has therapeutic impact.
[17629962] Trends Pharmacol Sci 28(8): 390-6 (2007)
2007  
51
Neoceptors: reengineering GPCRs to recognize tailored ligands.
[17280720] Trends Pharmacol Sci 28(3): 111-6 (2007)
2010  
52
Therapeutic antibodies directed at G protein-coupled receptors.
[20864805] MAbs 2(6): 594-606 (2010)
2011  
53
G-protein coupled receptor and kinase targets: advances in drug discovery from molecular to clinical.
[21806373] Future Med Chem 3(9): 1097-100 (2011)
2010  
54
Beyond desensitization: physiological relevance of arrestin-dependent signaling.
[20427692] Pharmacol Rev 62(2): 305-30 (2010)
2010  
55
Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery.
[20392808] Pharmacol Rev 62(2): 265-304 (2010)
2007  
56
International Union of Basic and Clinical Pharmacology. LXVII. Recommendations for the recognition and nomenclature of G protein-coupled receptor heteromultimers.
[17329545] Pharmacol Rev 59(1): 5-13 (2007)
2009  
57
Rhodopsin and the others: a historical perspective on structural studies of G protein-coupled receptors.
[20028316] Curr Pharm Des 15(35): 3994-4002 (2009)
2009  
58
Unraveling the structure and function of G protein-coupled receptors through NMR spectroscopy.
[20028318] Curr Pharm Des 15(35): 4003-16 (2009)
2010  
59
Teaching old receptors new tricks: biasing seven-transmembrane receptors.
[20431569] Nat Rev Drug Discov 9(5): 373-86 (2010)
2008  
60
Activation of G protein-coupled receptors: beyond two-state models and tertiary conformational changes.
[17848137] Annu Rev Pharmacol Toxicol 48(-): 107-41 (2008)
2010  
61
G protein-coupled receptor-associated sorting protein 1 regulates the postendocytic sorting of seven-transmembrane-spanning G protein-coupled receptors.
[20693822] Pharmacology 86(1): 22-9 (2010)
2009  
62
Molecular mechanisms of go signaling.
[19212138] Neurosignals 17(1): 23-41 (2009)
2011  
63
GPCR oligomers in pharmacology and signaling.
[21619615] Mol Brain 4(1): 20 (2011)
2004  
64
Oligomerization of G protein-coupled receptors: past, present, and future.
[15595821] Biochemistry 43(50): 15643-56 (2004)
2010  
65
The year in G protein-coupled receptor research.
[20019124] Mol Endocrinol 24(1): 261-74 (2010)
2010  
66
Imaging of persistent cAMP signaling by internalized G protein-coupled receptors.
[20378719] J Mol Endocrinol 45(1): 1-8 (2010)
2008  
67
G protein betagamma subunits as targets for small molecule therapeutic development.
[18537559] Comb Chem High Throughput Screen 11(5): 382-95 (2008)
2010  
68
The quest to understand heterotrimeric G protein signaling.
[20520658] Nat Struct Mol Biol 17(6): 650-2 (2010)
2009  
69
The R7 RGS protein family: multi-subunit regulators of neuronal G protein signaling.
[19521673] Cell Biochem Biophys 54(1-3): 33-46 (2009)
2009  
70
G-protein-coupled receptor structures were not built in a day.
[19536805] Protein Sci 18(7): 1335-42 (2009)
2010  
71
Allostery at G protein-coupled receptor homo- and heteromers: uncharted pharmacological landscapes.
[21079041] Pharmacol Rev 62(4): 701-25 (2010)

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