Ion channel (BASKET)

Ion channels in vascular smooth muscle. Physiology and pharmacology.
[7505535] Anesthesiology 79(6): 1392-401 (1993)

Dynamic selectivity filters in ion channels.
[10482233] Neuron 23(4): 653-8 (1999)

An ingenious filter: the structural basis for ion channel selectivity.
[9620686] Neuron 20(5): 821-3 (1998)

Ion channels: too complex for rational drug design?
[8630249] Neuron 16(5): 913-9 (1996)

A structural vignette common to voltage sensors and conduction pores: canaliculi.
[8607990] Neuron 16(4): 717-22 (1996)

Pore loops: an emerging theme in ion channel structure.
[7538310] Neuron 14(5): 889-92 (1995)

Charge selectivity of the Cys-loop family of ligand-gated ion channels.
[15663470] J Neurochem 92(2): 217-25 (2005)

Potassium, sodium, calcium and glutamate-gated channels: pore architecture and ligand action.
[14756799] J Neurochem 88(4): 782-99 (2004)

Ion channel diseases of the central nervous system.
[11474425] CNS Drug Rev 7(2): 214-40 (2001)

Pharmacological rescue of mutant ion channels.
[12123759] Cardiovasc Res 55(2): 229-32 (2002)

From genes to channels: normal mechanisms.
[10533570] Cardiovasc Res 42(2): 318-26 (1999)

A list of vertebrate cardiac ionic currents nomenclature, properties, function and cloned equivalents.
[8881508] Cardiovasc Res 32(3): 455-81 (1996)

Arachidonic acid and ion channels: an update.
[18552881] Br J Pharmacol 155(1): 4-16 (2008)

International Union of Pharmacology. LI. Nomenclature and structure-function relationships of cyclic nucleotide-regulated channels.
[16382102] Pharmacol Rev 57(4): 455-62 (2005)

International Union of Pharmacology. L. Nomenclature and structure-function relationships of CatSper and two-pore channels.
[16382101] Pharmacol Rev 57(4): 451-4 (2005)

Overview of molecular relationships in the voltage-gated ion channel superfamily.
[16382097] Pharmacol Rev 57(4): 387-95 (2005)

International Union of Pharmacology. XLII. Compendium of voltage-gated ion channels: cyclic nucleotide-modulated channels.
[14657416] Pharmacol Rev 55(4): 587-9 (2003)

Ion channels-related diseases.
[11310970] Acta Biochim Pol 47(3): 685-703 (2000)

Understanding ion channel selectivity and gating and their role in cellular signalling.
[17216034] Mol Biosyst 2(11): 527-35 (2006)

Searching for interesting channels: pairing selection and molecular evolution methods to study ion channel structure and function.
[19603113] Mol Biosyst 5(8): 802-10 (2009)

Trafficking and cellular distribution of voltage-gated sodium channels.
[17988224] Traffic 9(1): 17-26 (2008)

Supramolecular assemblies and localized regulation of voltage-gated ion channels.
[19342611] Physiol Rev 89(2): 411-52 (2009)

Cyclic nucleotide-gated ion channels.
[12087135] Physiol Rev 82(3): 769-824 (2002)

The voltage sensor in voltage-dependent ion channels.
[10747201] Physiol Rev 80(2): 555-92 (2000)

Voltage-gated ion channels and hereditary disease.
[10508236] Physiol Rev 79(4): 1317-72 (1999)

Mechanosensitive ion channels: molecules of mechanotransduction.
[15159450] J Cell Sci 117(Pt 12): 2449-60 (2004)

Pore stability and gating in voltage-activated calcium channels.
[18849656] Channels (Austin) 2(2): 61-9 (2008)

Ion channel regulation by Ras, Rho, and Rab small GTPases.
[17959838] Exp Biol Med (Maywood) 232(10): 1258-65 (2007)

Ion pumps in polarized cells: sorting and regulation of the Na+, K+- and H+, K+-ATPases.
[11404365] J Biol Chem 276(32): 29617-20 (2001)

Crystallographic analyses of ion channels: lessons and challenges.
[10625597] J Biol Chem 275(2): 713-6 (2000)

Mechanism of ion transport across membranes. Bacteriorhodopsin as a prototype for proton pumps.
[9395442] J Biol Chem 272(50): 31209-12 (1997)

Ion channel genes and human neurological disease: recent progress, prospects, and challenges.
[10220366] Proc Natl Acad Sci U S A 96(9): 4759-66 (1999)

Voltage-gated ion channels.
[15668152] Curr Biol 15(2): R44-7 (2005)

Channel gating: twist to open.
[11369249] Curr Biol 11(9): R364-6 (2001)

Ion channels: structure of a molecular brake.
[10074448] Curr Biol 9(5): R173-5 (1999)

Ion-channel gating. Twist to open.
[7627551] Curr Biol 5(4): 373-5 (1995)

Structure of cation channels, revealed by single particle electron microscopy.
[15111105] FEBS Lett 564(3): 251-6 (2004)

L-type voltage-gated calcium channels: understanding function through structure.
[15111104] FEBS Lett 564(3): 245-50 (2004)

Structural basis for ion conduction and gating in ClC chloride channels.
[15111101] FEBS Lett 564(3): 229-33 (2004)

Ion channel gating: insights via molecular simulations.
[14630324] FEBS Lett 555(1): 85-90 (2003)

Voltage gating is a fundamental feature of porin and toxin beta-barrel membrane channels.
[9714531] FEBS Lett 431(3): 305-8 (1998)

Ion channel regulation by calmodulin binding.
[8070555] FEBS Lett 350(2-3): 155-8 (1994)

Structure, transmembrane topology and helix packing of P-type ion pumps.
[8206155] FEBS Lett 346(1): 32-8 (1994)

Ion channels: molecular basis of ion selectivity.
[7685711] FEBS Lett 325(1-2): 100-3 (1993)

Computational studies of membrane channels.
[15296727] Structure 12(8): 1343-51 (2004)

New structural perspectives on K(+) channel gating.
[12176380] Structure 10(8): 1027-9 (2002)

Noninvasive measurement of hydrogen and potassium ion flux from single cells and epithelial structures.
[11121371] Am J Physiol Cell Physiol 280(1): C1-11 (2001)

Properties of cytotoxic peptide-formed ion channels.
[10837335] Am J Physiol Cell Physiol 278(6): C1063-87 (2000)

Regulation of ion channels by protein tyrosine phosphorylation.
[11668044] Am J Physiol Heart Circ Physiol 281(5): H1835-62 (2001)

Regulation of ion channel structure and function by reactive oxygen-nitrogen species.
[14604848] Am J Physiol Lung Cell Mol Physiol 285(6): L1184-9 (2003)

Complex roles of PIP2 in the regulation of ion channels and transporters.
[17928411] Am J Physiol Renal Physiol 293(6): F1761-5 (2007)

Interaction of epithelial ion channels with the actin-based cytoskeleton.
[16926444] Am J Physiol Renal Physiol 291(6): F1113-22 (2006)

The neuronal channelopathies.
[12023309] Brain 125(Pt 6): 1177-95 (2002)

Transient receptor potential channels in cardiovascular function and disease.
[16857972] Circ Res 99(2): 119-31 (2006)

Regulation of ion channel expression.
[15087427] Circ Res 94(7): 874-83 (2004)

Inward rectification and implications for cardiac excitability.
[8603491] Circ Res 78(1): 1-7 (1996)

Molecular basis of permeation in voltage-gated ion channels.
[7679332] Circ Res 72(3): 491-6 (1993)

Ion channels: structural bioinformatics and modelling.
[12351578] Hum Mol Genet 11(20): 2425-33 (2002)

Phenotype variation and newcomers in ion channel disorders.
[9300659] Hum Mol Genet 6(10): 1679-85 (1997)

Molecular control of iron transport.
[17229910] J Am Soc Nephrol 18(2): 394-400 (2007)

Channelopathies: ion channel defects linked to heritable clinical disorders.
[11015449] J Med Genet 37(10): 729-40 (2000)

Ion channels and neurological disease: DNA based diagnosis is now possible, and ion channels may be important in common paroxysmal disorders.
[9771758] J Neurol Neurosurg Psychiatry 65(4): 427-31 (1998)

Inherited neuronal ion channelopathies: new windows on complex neurological diseases.
[19005038] J Neurosci 28(46): 11768-77 (2008)

Neurological channelopathies.
[15640425] Postgrad Med J 81(951): 20-32 (2005)

Oxygen sensing by ion channels.
[9027721] Kidney Int 51(2): 454-61 (1997)

Diagnostics and therapy of muscle channelopathies--Guidelines of the Ulm Muscle Centre.
[19472919] Acta Myol 27(-): 98-113 (2008)

Tarui disease and distal glycogenoses: clinical and genetic update.
[18421897] Acta Myol 26(2): 105-7 (2007)

Counting channels: a tutorial guide on ion channel fluctuation analysis.
[12444005] Adv Physiol Educ 26(1-4): 327-41 (2002)

Ion homeostasis, channels, and transporters: an update on cellular mechanisms.
[15545343] Adv Physiol Educ 28(1-4): 143-54 (2004)

In the beginning, there was the cell: cellular homeostasis.
[15545341] Adv Physiol Educ 28(1-4): 135-8 (2004)

Channels active in the excitability of nerves and skeletal muscles across the neuromuscular junction: basic function and pathophysiology.
[18539851] Adv Physiol Educ 32(2): 127-35 (2008)

An ion channel 'addicted' to ether, alcohol and cocaine: the HERG potassium channel.
[11744008] Cardiovasc Res 53(1): 6-8 (2002)

Ion channels in death and differentiation of prostate cancer cells.
[17479110] Cell Death Differ 14(7): 1295-304 (2007)

Ion channel regulation by protein palmitoylation.
[21216969] J Biol Chem 286(11): 8709-16 (2011)

Use of venom peptides to probe ion channel structure and function.
[20189991] J Biol Chem 285(18): 13315-20 (2010)

A marriage of convenience: beta-subunits and voltage-dependent K+ channels.
[17606609] J Biol Chem 282(34): 24485-9 (2007)

Cyclic nucleotide-regulated cation channels.
[19054768] J Biol Chem 284(14): 9017-21 (2009)

Revealing the structural basis of action of hERG potassium channel activators and blockers.
[20643767] J Physiol 588(Pt 17): 3157-67 (2010)

Significance of SGK1 in the regulation of neuronal function.
[20530112] J Physiol 588(Pt 18): 3349-54 (2010)

Gating of two pore domain potassium channels.
[20566661] J Physiol 588(Pt 17): 3149-56 (2010)

Lipid microdomains and the regulation of ion channel function.
[20519314] J Physiol 588(Pt 17): 3169-78 (2010)

Neurological channelopathies: new insights into disease mechanisms and ion channel function.
[20375141] J Physiol 588(Pt 11): 1823-7 (2010)

Voltage-sensor mutations in channelopathies of skeletal muscle.
[20156847] J Physiol 588(Pt 11): 1887-95 (2010)

Muscle channelopathies: does the predicted channel gating pore offer new treatment insights for hypokalaemic periodic paralysis?
[20123788] J Physiol 588(Pt 11): 1879-86 (2010)

Store-operated channels: mechanisms and function.
[18593888] J Physiol 586(13): 3033 (2008)

Functional roles of cytoplasmic loops and pore lining transmembrane helices in the voltage-dependent inactivation of HVA calcium channels.
[12815185] J Physiol 554(Pt 2): 263-73 (2004)

Physiological modulation of inactivation in L-type Ca2+ channels: one switch.
[12824441] J Physiol 554(Pt 2): 275-83 (2004)

Atomic structure and dynamics of pentameric ligand-gated ion channels: new insight from bacterial homologues.
[19995852] J Physiol 588(Pt 4): 565-72 (2010)

The gating isomerization of neuromuscular acetylcholine receptors.
[19933754] J Physiol 588(Pt 4): 573-86 (2010)

Advances and hold-ups in the study of structure, function and regulation of Cys-loop ligand-gated ion channels and receptors.
[20173078] J Physiol 588(Pt 4): 555-6 (2010)

Voltage-sensing phosphatase: actions and potentials.
[19074969] J Physiol 587(Pt 3): 513-20 (2009)

Regulation of neural KCNQ channels: signalling pathways, structural motifs and functional implications.
[18238808] J Physiol 586(7): 1811-21 (2008)

Targeting ion channels for drug discovery.
[20350493] Discov Med 9(46): 253-60 (2010)

Hyperpolarization-activated cation channels: from genes to function.
[19584315] Physiol Rev 89(3): 847-85 (2009)

Integrating the discovery pipeline for novel compounds targeting ion channels.
[18678277] Curr Opin Chem Biol 12(4): 441-7 (2008)

Ion channelopathies in endocrinology: recent genetic findings and pathophysiological insights.
[21340151] Arq Bras Endocrinol Metabol 54(8): 673-81 (2010)

Ion channels versus ion pumps: the principal difference, in principle.
[19339978] Nat Rev Mol Cell Biol 10(5): 344-52 (2009)

Activation and modulation of ligand-gated ion channels.
[15119941] Physiol Res 53 Suppl 1(-): S103-13 (2004)

Mechanosensitivity of ion channels based on protein-lipid interactions.
[20356872] J R Soc Interface 7 Suppl 3(-): S307-20 (2010)

Peptide Neurotoxins that Affect Voltage-Gated Calcium Channels: A Close-Up on ω-Agatoxins.
[22069688] Toxins (Basel) 3(1): 17-42 (2011)

The gates of ion channels and enzymes.
[19926290] Trends Biochem Sci 35(3): 179-85 (2010)

Forward trafficking of ion channels: what the clinician needs to know.
[20621620] Heart Rhythm 7(8): 1135-40 (2010)

Visualizing ion channel dynamics at the plasma membrane.
[18456207] Heart Rhythm 5(6 Suppl): S7-11 (2008)

Emerging concepts in the pharmacogenomics of arrhythmias: ion channel trafficking.
[20670193] Expert Rev Cardiovasc Ther 8(8): 1161-73 (2010)

Cardiac ankyrins in health and disease.
[19394342] J Mol Cell Cardiol 47(2): 203-9 (2009)

Regulation of epithelial ion channels by Rab GTPases.
[17084813] Biochem Biophys Res Commun 351(3): 582-7 (2006)

Unraveling the mechanisms of rare diseases.
[18560623] Drug News Perspect 21(4): 233-40 (2008)

Transient receptor potential channels on sensory nerves.
[19655110] Handb Exp Pharmacol (194): 261-81 (2009)

Ca2+ channels and pulmonary endothelial permeability: insights from study of intact lung and chronic pulmonary hypertension.
[17085430] Microcirculation 13(8): 725-39 (2006)

Bringing ion channel crystal structures into sharper focus with computer modeling: examples from mechanosensitive channels.
[21426108] Future Med Chem 2(6): 909-13 (2010)

Renaissance of ion channel research and drug discovery by patch clamp automation.
[21426196] Future Med Chem 2(5): 691-5 (2010)

Understanding ion channels using computational approaches.
[21426197] Future Med Chem 2(5): 697-701 (2010)

From understanding cellular function to novel drug discovery: the role of planar patch-clamp array chip technology.
[22007170] Front Pharmacol 2(-): 51 (2011)

Ca permeable AMPA channels in diseases of the nervous system.
[22102834] Front Mol Neurosci 4(-): 42 (2011)

Calcium-permeable AMPA receptors in the retina.
[21991245] Front Mol Neurosci 4(-): 27 (2011)

Ion channel voltage sensors: structure, function, and pathophysiology.
[20869590] Neuron 67(6): 915-28 (2010)

A nomenclature for ligand-gated ion channels.
[18655795] Neuropharmacology 56(1): 2-5 (2009)

Circadian regulation of ion channels and their functions.
[19549279] J Neurochem 110(4): 1150-69 (2009)

Ca(2+)-regulated ion channels.
[22026996] BMB Rep 44(10): 635-46 (2011)

Direct effect of protein kinase C inhibitors on cardiovascular ion channels.
[21944247] BMB Rep 44(9): 559-65 (2011)

Sorting out MIC, TRP, and CRAC ion channels.
[12149282] J Gen Physiol 120(2): 217-20 (2002)

Coupled movements in voltage-gated ion channels.
[12356847] J Gen Physiol 120(4): 449-53 (2002)

Molecular models of voltage sensing.
[12356848] J Gen Physiol 120(4): 455-63 (2002)

The search is on for the voltage sensor-to-gate coupling.
[12356850] J Gen Physiol 120(4): 475-81 (2002)

Structural studies of ion selectivity in tetrameric cation channels.
[21518828] J Gen Physiol 137(5): 397-403 (2011)

Origins of ion selectivity in potassium channels from the perspective of channel block.
[21518829] J Gen Physiol 137(5): 405-13 (2011)

Ion selectivity in channels and transporters.
[21518830] J Gen Physiol 137(5): 415-26 (2011)

Thermodynamics of ion selectivity in the KcsA K+ channel.
[21518831] J Gen Physiol 137(5): 427-33 (2011)

Mining recent brain proteomic databases for ion channel phosphosite nuggets.
[21149544] J Gen Physiol 137(1): 3-16 (2011)

Gating mechanism of KATP channels: function fits form.
[14581579] J Gen Physiol 122(5): 471-80 (2003)

How highly charged anionic lipids bind and regulate ion channels.
[18411329] J Gen Physiol 131(5): 431-8 (2008)

Cholesterol and ion channels.
[20213557] Subcell Biochem 51(-): 509-49 (2010)

Forty years of monensin for the control of coccidiosis in poultry.
[20709963] Poult Sci 89(9): 1788-801 (2010)

PIP2 is a necessary cofactor for ion channel function: how and why?
[18573078] Annu Rev Biophys 37(-): 175-95 (2008)

Ion channels as targets for cancer therapy.
[21760973] Int J Physiol Pathophysiol Pharmacol 3(2): 156-66 (2011)

Ion channels and pores, made from scratch.
[17882329] Mol Biosyst 3(10): 658-66 (2007)

Optical switches and triggers for the manipulation of ion channels and pores.
[17882331] Mol Biosyst 3(10): 686-704 (2007)

Population patch clamp electrophysiology: a breakthrough technology for ion channel screening.
[17882333] Mol Biosyst 3(10): 714-22 (2007)

Understanding and manipulating channels and pores.
[17882326] Mol Biosyst 3(10): 645-7 (2007)

Interactions of connexins with other membrane channels and transporters.
[17475311] Prog Biophys Mol Biol 94(1-2): 233-44 (2007)

Caveolae, ion channels and cardiac arrhythmias.
[19351512] Prog Biophys Mol Biol 98(2-3): 149-60 (2008)

Ultra-rapid delayed rectifier channels: molecular basis and therapeutic implications.
[21159668] Cardiovasc Res 89(4): 776-85 (2011)

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