Ion channel (TRP Family)

TRP channels of intracellular membranes.
[20132470] J Neurochem 113(2): 313-28 (2010)

ThermoTRP channels in nociceptors: taking a lead from capsaicin receptor TRPV1.
[19305786] Curr Neuropharmacol 6(1): 21-38 (2008)

N-(p-amylcinnamoyl)anthranilic acid (ACA): a phospholipase A(2) inhibitor and TRP channel blocker.
[17445088] Cardiovasc Drug Rev 25(1): 61-75 (2007)

International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.
[16382100] Pharmacol Rev 57(4): 427-50 (2005)

International Union of Pharmacology. XLIII. Compendium of voltage-gated ion channels: transient receptor potential channels.
[14657417] Pharmacol Rev 55(4): 591-6 (2003)

Transient receptor potential melastatin 6 and 7 channels, magnesium transport, and vascular biology: implications in hypertension.
[18192217] Am J Physiol Heart Circ Physiol 294(3): H1103-18 (2008)

Regulation of TRPV5 and TRPV6 by associated proteins.
[16682485] Am J Physiol Renal Physiol 290(6): F1295-302 (2006)

TRPV4: a new target for the hypertension-related kinases WNK1 and WNK4.
[16467131] Am J Physiol Renal Physiol 290(6): F1303-4 (2006)

TRP channels and the regulation of vascular permeability: new insights from the lung microvasculature.
[17068297] Circ Res 99(9): 915-7 (2006)

Unexpected role of TRPC6 channel in familial nephrotic syndrome: does it have clinical implications?
[16396961] J Am Soc Nephrol 17(2): 378-87 (2006)

The transient receptor potential superfamily of ion channels.
[15213256] J Am Soc Nephrol 15(7): 1690-9 (2004)

TRPA1: the central molecule for chemical sensing in pain pathway?
[18234879] J Neurosci 28(5): 1019-21 (2008)

Slit or pore? A mutation of the ion channel TRPC6 causes FSGS.
[15998650] Nephrol Dial Transplant 20(9): 1777-9 (2005)

Targeting TRPV1 as an alternative approach to narcotic analgesics to treat chronic pain conditions.
[20440589] AAPS J 12(3): 361-70 (2010)

Non-selective cation channels, transient receptor potential channels and ischemic stroke.
[17446049] Biochim Biophys Acta 1772(8): 947-57 (2007)

TRPC channel modulation in podocytes-inching toward novel treatments for glomerular disease.
[21161284] Pediatr Nephrol 26(7): 1057-64 (2011)

The pathological role of transient receptor potential channels in heart disease.
[19202304] Circ J 73(3): 419-27 (2009)

Molecular diversity of receptor operated channels in vascular smooth muscle: a role for heteromultimeric TRP channels?
[16794194] Circ Res 98(12): 1462-4 (2006)

Multiple activation mechanisms of store-operated TRPC channels in smooth muscle cells.
[17615095] J Physiol 583(Pt 1): 25-36 (2007)

Understanding the role of voltage gating of polymodal TRP channels.
[18056113] J Physiol 585(Pt 2): 321-2 (2007)

TRP channels and lipids: from Drosophila to mammalian physiology.
[16990401] J Physiol 578(Pt 1): 9-24 (2007)

TRP channels entering the structural era.
[18535090] J Physiol 586(Pt 15): 3565-75 (2008)

Gating of TRP channels: a voltage connection?
[15878939] J Physiol 567(Pt 1): 35-44 (2005)

The developing relationship between receptor-operated and store-operated calcium channels in smooth muscle.
[11786473] Br J Pharmacol 135(1): 1-13 (2002)

Pharmacology of transient receptor potential melastatin channels in the vasculature.
[20233227] Br J Pharmacol 159(8): 1559-71 (2010)

Darier's disease: a calcium-signaling perspective.
[18049860] Cell Mol Life Sci 65(2): 205-11 (2008)

TRP channel proteins and signal transduction.
[11917094] Physiol Rev 82(2): 429-72 (2002)

Transient receptor potential cation channels in disease.
[17237345] Physiol Rev 87(1): 165-217 (2007)

Cellular functions of transient receptor potential channels.
[20399884] Int J Biochem Cell Biol 42(9): 1430-45 (2010)

An endoplasmic reticulum/plasma membrane junction: STIM1/Orai1/TRPCs.
[19944100] FEBS Lett 584(10): 2022-7 (2010)

Role of TRPV ion channels in sensory transduction of osmotic stimuli in mammals.
[17350992] Exp Physiol 92(3): 507-12 (2007)

Transient receptor potential (TRP) channels as drug targets for diseases of the digestive system.
[21420431] Pharmacol Ther 131(1): 142-70 (2011)

TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades
[21204492] (): (2007)

TRP channels in the digestive system.
[20932260] Curr Pharm Biotechnol 12(1): 24-34 (2011)

The Involvement of TRP Channels in Bone Homeostasis.
[22934090] Front Endocrinol (Lausanne) 3(): 99 (2012)

Canonical transient receptor potential (TRPC) 1 acts as a negative regulator for vanilloid TRPV6 mediated Ca2+ influx.
[22932896] J Biol Chem (): (2012)

The selectivity filter of the cation channel TRPM4.
[15845551] J Biol Chem 280(24): 22899-906 (2005)

Ca2+-selective transient receptor potential V channel architecture and function require a specific ankyrin repeat.
[15192090] J Biol Chem 279(33): 34456-63 (2004)

Outer pore architecture of a Ca2+-selective TRP channel.
[14736889] J Biol Chem 279(15): 15223-30 (2004)

Expression of CaT-like, a novel calcium-selective channel, correlates with the malignancy of prostate cancer.
[11278579] J Biol Chem 276(22): 19461-8 (2001)

A rat kidney-specific calcium transporter in the distal nephron.
[10875938] J Biol Chem 275(36): 28186-94 (2000)

Homo- and heteromeric assembly of TRPV channel subunits.
[15713749] J Cell Sci 118(Pt 5): 917-28 (2005)

Vanilloid and melastatin transient receptor potential channels in vascular smooth muscle.
[20536737] Microcirculation 17(4): 237-49 (2010)

Pharmacology of vanilloid transient receptor potential cation channels.
[19297520] Mol Pharmacol 75(6): 1262-79 (2009)

Permeation and selectivity of TRP channels.
[16460288] Annu Rev Physiol 68(): 685-717 (2006)

Assembly domains in TRP channels.
[17233607] Biochem Soc Trans 35(Pt 1): 84-5 (2007)

A comparison of the genes coding for canonical TRP channels and their M, V and P relatives.
[12765687] Cell Calcium 33(5-6): 419-32 (2003)

TRP proteins and cancer.
[17029734] Cell Signal 19(3): 617-24 (2007)

Vanilloid transient receptor potential cation channels: an overview.
[18220815] Curr Pharm Des 14(1): 18-31 (2008)

Tissue-specific expression of TRP channel genes in the mouse and its variation in three different mouse strains.
[16787531] BMC Genomics 7(): 159 (2006)

Molecular basis of epithelial Ca2+ and Mg2+ transport: insights from the TRP channel family.
[21041532] J Physiol 589(Pt 7): 1535-42 (2011)

Regulation of TRP channels: a voltage-lipid connection.
[17233613] Biochem Soc Trans 35(Pt 1): 105-8 (2007)

The TRP channel superfamily: insights into how structure, protein-lipid interactions and localization influence function.
[17233605] Biochem Soc Trans 35(Pt 1): 77-80 (2007)

TRP channels in kidney disease.
[17346947] Biochim Biophys Acta 1772(8): 928-36 (2007)

Transient receptor potential channels in the kidney: calcium signaling, transport and beyond.
[16523421] J Nephrol 19(1): 21-9 (2006)

The role of transient receptor potential channels in kidney disease.
[19546862] Nat Rev Nephrol 5(8): 441-9 (2009)

Regulation of transient receptor potential (TRP) channels by phosphoinositides.
[17479281] Pflugers Arch 455(1): 157-68 (2007)

Regulation of TRP channels by N-linked glycosylation.
[17215147] Semin Cell Dev Biol 17(6): 630-7 (2006)

TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades
[21204494] (): (2007)

TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades
[21204489] (): (2007)

Acid sensing by visceral afferent neurones.
[20456281] Acta Physiol (Oxf) 201(1): 63-75 (2011)

Thermosensitive transient receptor potential channels in vagal afferent neurons of the mouse.
[14726308] Am J Physiol Gastrointest Liver Physiol 286(6): G983-91 (2004)

Expression of store-operated Ca2+ entry and transient receptor potential canonical and vanilloid-related proteins in rat distal pulmonary venous smooth muscle.
[20693314] Am J Physiol Lung Cell Mol Physiol 299(5): L621-30 (2010)

Functional expression of transient receptor potential melastatin- and vanilloid-related channels in pulmonary arterial and aortic smooth muscle.
[16399784] Am J Physiol Lung Cell Mol Physiol 290(6): L1267-76 (2006)

Expression and distribution of transient receptor potential (TRP) channels in bladder epithelium.
[20943764] Am J Physiol Renal Physiol 300(1): F49-59 (2011)

Functional characterization of transient receptor potential channels in mouse urothelial cells.
[20015940] Am J Physiol Renal Physiol 298(3): F692-701 (2010)

Functional TRP and ASIC-like channels in cultured urothelial cells from the rat.
[19158342] Am J Physiol Renal Physiol 296(4): F892-901 (2009)

Role of transient receptor potential and acid-sensing ion channels in peripheral inflammatory pain.
[20179512] Anesthesiology 112(3): 729-41 (2010)

TRP channels in neurogastroenterology: opportunities for therapeutic intervention.
[20804496] Br J Pharmacol 162(1): 18-37 (2011)

Transient receptor potential channels in cardiovascular function and disease.
[16857972] Circ Res 99(2): 119-31 (2006)

Recent developments in vascular endothelial cell transient receptor potential channels.
[16254217] Circ Res 97(9): 853-63 (2005)

The role of thermosensitive TRP (transient receptor potential) channels in insulin secretion.
[21785227] Endocr J 58(12): 1021-8 (2011)

Role of TRP channels in pain sensation.
[21290319] Adv Exp Med Biol 704(): 615-36 (2011)

TRP channels in endothelial function and dysfunction.
[17434294] Biochim Biophys Acta 1772(8): 907-14 (2007)

Role of TRPV receptors in respiratory diseases.
[17346945] Biochim Biophys Acta 1772(8): 915-27 (2007)

TRP channels: targets for the relief of pain.
[17321113] Biochim Biophys Acta 1772(8): 989-1003 (2007)

The role of the transient receptor potential (TRP) superfamily of cation-selective channels in the management of the overactive bladder.
[21156013] BJU Int 106(8): 1114-27 (2010)

Mechanotransduction by TRP channels: general concepts and specific role in the vasculature.
[19842065] Cell Biochem Biophys 56(1): 1-18 (2010)

TRPV channels as temperature sensors.
[12765693] Cell Calcium 33(5-6): 479-87 (2003)

Vertebrate and invertebrate TRPV-like mechanoreceptors.
[12765692] Cell Calcium 33(5-6): 471-8 (2003)

Transient receptor potential (TRP) channels, vascular tone and autoregulation of cerebral blood flow.
[18215190] Clin Exp Pharmacol Physiol 35(9): 1116-20 (2008)

TRP channel antagonists for pain--opportunities beyond TRPV1.
[19579171] Curr Opin Investig Drugs 10(7): 655-63 (2009)

Transient receptor potential ion channels as targets for the discovery of pain therapeutics.
[15675603] Curr Opin Investig Drugs 6(1): 48-57 (2005)

The role of natural products in the ligand deorphanization of TRP channels.
[18220814] Curr Pharm Des 14(1): 2-17 (2008)

Therapeutic targeting of TRP channels--the TR(i)P to pain relief.
[21671881] Curr Top Med Chem 11(17): 2118-30 (2011)

Transient receptor potential channels in endothelium: solving the calcium entry puzzle?
[12699072] Endothelium 10(1): 5-15 (2003)

Advances in modulating thermosensory TRP channels.
[22835143] Expert Opin Ther Pat 22(9): 999-1017 (2012)

Newly emerging Ca2+ entry channel molecules that regulate the vascular tone.
[15268627] Expert Opin Ther Targets 8(4): 321-34 (2004)

TRPV channels' role in osmotransduction and mechanotransduction.
[17217074] Handb Exp Pharmacol (179): 473-87 (2007)

Sensing hot and cold with TRP channels.
[21591901] Int J Hyperthermia 27(4): 388-98 (2011)

TRPV channel expression in human skin and possible role in thermally induced cell death.
[21099694] J Burn Care Res 32(1): 150-9 (2011)

Endothelium-dependent cerebral artery dilation mediated by transient receptor potential and Ca2+-activated K+ channels.
[20729757] J Cardiovasc Pharmacol 57(2): 148-53 (2011)

Distribution and expression of non-neuronal transient receptor potential (TRPV) ion channels in rosacea.
[22189789] J Invest Dermatol 132(4): 1253-62 (2012)

Thermosensation and pain.
[15362149] J Neurobiol 61(1): 3-12 (2004)

Transient receptor potential vanilloid channels functioning in transduction of osmotic stimuli.
[17170210] J Endocrinol 191(3): 515-23 (2006)

Evolution of thermoTRP ion channel homologs in vertebrates.
[16926268] Physiol Genomics 27(3): 219-30 (2006)

Topical review. Dental pain and odontoblasts: facts and hypotheses.
[21197505] J Orofac Pain 24(4): 335-49 (2010)

TRP channels and analgesia.
[22910182] Life Sci (): (2012)

Ca2+ channels and pulmonary endothelial permeability: insights from study of intact lung and chronic pulmonary hypertension.
[17085430] Microcirculation 13(8): 725-39 (2006)

Human odontoblasts express transient receptor protein and acid-sensing ion channel mechanosensor proteins.
[20836083] Microsc Res Tech 74(5): 457-63 (2011)

Expression of transient receptor potential (TRP) channels in human and murine osteoblast-like cells.
[19115145] Mol Membr Biol 26(3): 146-58 (2009)

Nitric oxide activates TRP channels by cysteine S-nitrosylation.
[16998480] Nat Chem Biol 2(11): 596-607 (2006)

From urgency to frequency: facts and controversies of TRPs in the lower urinary tract.
[21971315] Nat Rev Urol 8(11): 617-30 (2011)

On the origin of bladder sensing: Tr(i)ps in urology.
[17849480] Neurourol Urodyn 27(4): 264-73 (2008)

Pathological role of TRP channels in cardiovascular and respiratory diseases.
[19749483] Nihon Yakurigaku Zasshi 134(3): 127-30 (2009)

TRPV channels as thermosensory receptors in epithelial cells.
[15952037] Pflugers Arch 451(1): 160-7 (2005)

The mechanosensitive nature of TRPV channels.
[15909178] Pflugers Arch 451(1): 193-203 (2005)

TRP channel and cardiovascular disease.
[18508125] Pharmacol Ther 118(3): 337-51 (2008)

Cation channels of the transient receptor potential superfamily: their role in physiological and pathophysiological processes of smooth muscle cells.
[16842858] Pharmacol Ther 112(3): 744-60 (2006)

TRP channel gene expression in the mouse retina.
[22037305] Vision Res 51(23-24): 2440-52 (2011)

Herbal compounds and toxins modulating TRP channels.
[19305789] Curr Neuropharmacol 6(1): 79-96 (2008)

The emerging role of TRP channels in mechanisms of temperature and pain sensation.
[18615141] Curr Neuropharmacol 4(3): 183-96 (2006)

International Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel family.
[20716668] Pharmacol Rev 62(3): 381-404 (2010)

Transient receptor potential channels: targeting pain at the source.
[19116627] Nat Rev Drug Discov 8(1): 55-68 (2009)

TRP Channels as Sensors and Signal Integrators of Redox Status Changes.
[22016736] Front Pharmacol 2(-): 58 (2011)

Transient receptor potential vanilloid channels in hypertension, inflammation, and end organ damage: an imminent target of therapy for cardiovascular disease?
[18520720] Curr Opin Cardiol 23(4): 356-63 (2008)

TRPC channels and their implication in neurological diseases.
[20201820] CNS Neurol Disord Drug Targets 9(1): 94-104 (2010)

Mechanism of Ca(2+)-dependent desensitization in TRP channels.
[18849652] Channels (Austin) 2(2): 125-9 (2008)

TRPC channels as STIM1-regulated SOCs.
[19574740] Channels (Austin) 3(4): 221-5 (2009)

Multiple unbiased prospective screens identify TRP channels and their conserved gating elements.
[18955590] J Gen Physiol 132(5): 481-6 (2008)

Divide and conquer: high resolution structural information on TRP channel fragments.
[19237587] J Gen Physiol 133(3): 231-7 (2009)

Hot on the trail of TRP channel structure.
[19237588] J Gen Physiol 133(3): 239-44 (2009)

TRP channels and Ca2+ signaling.
[16806461] Cell Calcium 40(3): 261-75 (2006)

TRPC channels as STIM1-regulated store-operated channels.
[17517433] Cell Calcium 42(2): 205-11 (2007)

Homer proteins in Ca2+ signaling by excitable and non-excitable cells.
[17618683] Cell Calcium 42(4-5): 363-71 (2007)

Phosphoinositide regulation of non-canonical transient receptor potential channels.
[19376575] Cell Calcium 45(6): 554-65 (2009)

Transient receptor potential channels meet phosphoinositides.
[18923420] EMBO J 27(21): 2809-16 (2008)

Insights on TRP channels from in vivo studies in Drosophila.
[16460287] Annu Rev Physiol 68(-): 649-84 (2006)

A primer on ankyrin repeat function in TRP channels and beyond.
[18414734] Mol Biosyst 4(5): 372-9 (2008)

Emerging concepts for the role of TRP channels in the cardiovascular system.
[21173080] J Physiol 589(Pt 7): 1527-34 (2011)

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