JNK

JNK pathway: diseases and therapeutic potential.
[17439715] Acta Pharmacol Sin 28(5): 601-8 (2007)

Uses for JNK: the many and varied substrates of the c-Jun N-terminal kinases.
[17158707] Microbiol Mol Biol Rev 70(4): 1061-95 (2006)

Signal transduction by the JNK group of MAP kinases.
[11057897] Cell 103(2): 239-52 (2000)

The c-jun kinase/stress-activated pathway: regulation, function and role in human disease.
[17306896] Biochim Biophys Acta 1773(8): 1341-8 (2007)

JNK2: a negative regulator of cellular proliferation.
[15611655] Cell Cycle 3(12): 1520-3 (2004)

PERK-dependent regulation of MDA-7/IL-24-induced autophagy in primary human glioma cells.
[18299661] Autophagy 4(4): 513-5 (2008)

MDA-7/IL-24 plus radiation enhance survival in animals with intracranial primary human GBM tumors.
[18376144] Cancer Biol Ther 7(6): 917-33 (2008)

MDA-7 regulates cell growth and radiosensitivity in vitro of primary (non-established) human glioma cells.
[15197348] Cancer Biol Ther 3(8): 739-51 (2004)

mda-7 (IL-24) Inhibits growth and enhances radiosensitivity of glioma cells in vitro via JNK signaling.
[14508103] Cancer Biol Ther 2(4): 347-53 (2003)

A novel pathway involving melanoma differentiation associated gene-7/interleukin-24 mediates nonsteroidal anti-inflammatory drug-induced apoptosis and growth arrest of cancer cells.
[17178890] Cancer Res 66(24): 11922-31 (2006)

MDA-7/IL-24-induced cell killing in malignant renal carcinoma cells occurs by a ceramide/CD95/PERK-dependent mechanism.
[19417161] Mol Cancer Ther 8(5): 1280-91 (2009)

Caspase-, cathepsin-, and PERK-dependent regulation of MDA-7/IL-24-induced cell killing in primary human glioma cells.
[18281515] Mol Cancer Ther 7(2): 297-313 (2008)

Cisplatin enhances protein kinase R-like endoplasmic reticulum kinase- and CD95-dependent melanoma differentiation-associated gene-7/interleukin-24-induced killing in ovarian carcinoma cells.
[19910452] Mol Pharmacol 77(2): 298-310 (2010)

mda-7/IL24 kills pancreatic cancer cells by inhibition of the Wnt/PI3K signaling pathways: identification of IL-20 receptor-mediated bystander activity against pancreatic cancer.
[15851011] Mol Ther 11(5): 724-33 (2005)

Adenovirus-mediated mda-7 (IL24) gene therapy suppresses angiogenesis and sensitizes NSCLC xenograft tumors to radiation.
[15194048] Mol Ther 9(6): 818-28 (2004)

Mechanisms of lysophosphatidylcholine-induced hepatocyte lipoapoptosis.
[21995961] Am J Physiol Gastrointest Liver Physiol 302(1): G77-84 (2012)

Ceramide induces p38 MAPK and JNK activation through a mechanism involving a thioredoxin-interacting protein-mediated pathway.
[18270325] Blood 111(8): 4365-74 (2008)

PLAB induction in fenretinide-induced apoptosis of ovarian cancer cells occurs via a ROS-dependent mechanism involving ER stress and JNK activation.
[19325135] Carcinogenesis 30(5): 824-31 (2009)

1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit colon cancer cell and tumor growth through activation of c-jun N-terminal kinase.
[18460448] Carcinogenesis 29(6): 1139-47 (2008)

Signaling by IL-1beta+IFN-gamma and ER stress converge on DP5/Hrk activation: a novel mechanism for pancreatic beta-cell apoptosis.
[19629134] Cell Death Differ 16(11): 1539-50 (2009)

Endoplasmic reticulum stress-induced apoptosis requires bax for commitment and Apaf-1 for execution in primary neurons.
[17218955] Cell Death Differ 14(5): 1011-9 (2007)

1,25(OH)2 vitamin d inhibits foam cell formation and suppresses macrophage cholesterol uptake in patients with type 2 diabetes mellitus.
[19667238] Circulation 120(8): 687-98 (2009)

Functional role of c-Jun-N-terminal kinase in feeding regulation.
[20022934] Endocrinology 151(2): 671-82 (2010)

JNK signaling in apoptosis.
[18931691] Oncogene 27(48): 6245-51 (2008)

The role of stress-activated protein kinase signaling in renal pathophysiology.
[18982195] Braz J Med Biol Res 42(1): 29-37 (2009)

The roles of ASK family proteins in stress responses and diseases.
[19389260] Cell Commun Signal 7(): 9 (2009)

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