Klotho

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Klotho

LE WE PMID CA

Klotho

1462

Klotho

beta Glucuronidase

BSPRY

Calbindin D28k

Calbindin D9k

Calcium (Hypercalciuria)

Calcium (Physiology renal)

Claudin2

Curcumin

CYP27B1 25OHD 1alpha hydroxylase

Diabetes mellitus (Involvement kidney)

Docosahexaenoic acid

Endoglycosidase F

FGF23

Galectin1

Kallikrein

Kidney (Tubulus Distal Convoluted)

Kir1 1 ROMK

Klotho

Lithocholic acid

NCX1

NPT2c

Osteocalcin

Osteopontin

Phosphorous

Pro Urine

RANKL

Receptor (RXR)

Transporter (Sodium and phosphate)

TRPV5

TRPV6

Vitamin D

2006 1	Klotho, an important new factor for the activity of Ca2+ channels, connecting calcium homeostasis, ageing and uraemia. [16627600] Nephrol Dial Transplant 21(7): 1770-2 (2006)
2007 2	Premature aging in klotho mutant mice: cause or consequence? [17353153] Ageing Res Rev 6(1): 73-9 (2007)
2009 3	Current understanding of klotho. [19022406] Ageing Res Rev 8(1): 43-51 (2009)
2009 4	Klotho and aging. [19230844] Biochim Biophys Acta 1790(10): 1049-58 (2009)
2009 5	Discovery of alpha-Klotho unveiled new insights into calcium and phosphate homeostasis. [19282648] Proc Jpn Acad Ser B Phys Biol Sci 85(3): 125-41 (2009)
2009 6	FGF23-mediated regulation of systemic phosphate homeostasis: is Klotho an essential player? [19019915] Am J Physiol Renal Physiol 296(3): F470-6 (2009)
2010 7	Reciprocal control of 1,25-dihydroxyvitamin D and FGF23 formation involving the FGF23/Klotho system. [20798257] Clin J Am Soc Nephrol 5(9): 1717-22 (2010)
2009 8	Klotho prevents renal calcium loss. [19713312] J Am Soc Nephrol 20(11): 2371-9 (2009)
2008 9	The beta-glucuronidase klotho exclusively activates the epithelial Ca2+ channels TRPV5 and TRPV6. [18495742] Nephrol Dial Transplant 23(11): 3397-402 (2008)
2008 10	Calcium and phosphate homeostasis: concerted interplay of new regulators. [18293139] Ann Med 40(2): 82-91 (2008)
2007 11	Concerted action of associated proteins in the regulation of TRPV5 and TRPV6. [17233615] Biochem Soc Trans 35(Pt 1): 115-9 (2007)
2012 12	Molecular Mechanisms of Vitamin D Action. [22782502] Calcif Tissue Int (): (2012)
2012 13	Characterization of vitamin D-deficient klotho-/- mice: do increased levels of serum 1,25(OH)2D3 cause disturbed calcium and phosphate homeostasis in klotho-/- mice? [22778178] Nephrol Dial Transplant (): (2012)
2005 14	The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel. [16239475] Science 310(5747): 490-3 (2005)
2009 15	Regulation of renal outer medullary potassium channel and renal K(+) excretion by Klotho. [19349416] Mol Pharmacol 76(1): 38-46 (2009)
2012 16	Regulation of ion channels by secreted Klotho. [22396165] Adv Exp Med Biol 728(): 100-6 (2012)
2007 17	Regulation of the epithelial calcium channel TRPV5 by extracellular factors. [17565273] Curr Opin Nephrol Hypertens 16(4): 319-24 (2007)
2006 18	Klotho as a regulator of fibroblast growth factor signaling and phosphate/calcium metabolism. [16775459] Curr Opin Nephrol Hypertens 15(4): 437-41 (2006)
2012 19	Targeted Deletion of Klotho in Kidney Distal Tubule Disrupts Mineral Metabolism. [22878961] J Am Soc Nephrol (): (2012)
2012 20	Decreased renal alpha-Klotho expression in early diabetic nephropathy in humans and mice and its possible role in urinary calcium excretion. [22217880] Kidney Int 81(6): 539-47 (2012)
2007 21	Klotho: an antiaging protein involved in mineral and vitamin D metabolism. [17332731] Kidney Int 71(8): 730-7 (2007)
2010 22	Klotho. [19730882] Pflugers Arch 459(2): 333-43 (2010)
2008 23	Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1. [18606998] Proc Natl Acad Sci U S A 105(28): 9805-10 (2008)
2010 24	Klotho and kidney disease. [21170871] J Nephrol 23 Suppl 16(-): S136-44 (2010)
2011 25	Klotho and the aging process. [21716585] Korean J Intern Med 26(2): 113-22 (2011)
2011 26	Klotho: an elixir of youth for the vasculature? [21164022] J Am Soc Nephrol 22(1): 5-7 (2011)

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