Lynch syndrome

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Lynch syndrome

LE WE PMID CA

Lynch syndrome

1675

Lynch Syndrom

Colon and rectum (Neoplasia)

Endometrium (Neoplasia)

Familial adenomatous polyposis

Genetics (Microsatellite)

Lynch syndrome

Medical ethics

MLH1

MSH2

MSH6

Neoplasia (Carcinogenesis)

Neoplasia (Inherited)

Physician patient relationship

PMS2

Prostate (Neoplasia)

2007 1	Review article: The Lynch syndrome (hereditary nonpolyposis colorectal cancer). [18081655] Aliment Pharmacol Ther 26 Suppl 2(-): 113-26 (2007)
2007 2	Review article: Detection and management of hereditary non-polyposis colorectal cancer (Lynch syndrome). [18081654] Aliment Pharmacol Ther 26 Suppl 2(-): 101-11 (2007)
2008 3	Thyroid cancer in a patient with a germline MSH2 mutation. Case report and review of the Lynch syndrome expanding tumour spectrum. [19706203] Hered Cancer Clin Pract 6(1): 15-21 (2008)
2004 4	Economic and Practical Factors in Diagnosing HNPCC Using Clinical Criteria, Immunohistochemistry and Microsatellite Instability Analysis. [20233461] Hered Cancer Clin Pract 2(4): 175-84 (2004)
2001 5	Microsatellite instability: application in hereditary non-polyposis colorectal cancer. [11300317] Ann Oncol 12(2): 151-60 (2001)
2006 6	Diagnostic approach and management of Lynch syndrome (hereditary nonpolyposis colorectal carcinoma): a guide for clinicians. [16870997] CA Cancer J Clin 56(4): 213-25 (2006)
2004 7	Hereditary nonpolyposis colorectal carcinoma (HNPCC) and HNPCC-like families: Problems in diagnosis, surveillance, and management. [14692024] Cancer 100(1): 53-64 (2004)
2002 8	Evaluation of screening strategy for detecting hereditary nonpolyposis colorectal carcinoma. [11920458] Cancer 94(4): 911-20 (2002)
1999 9	Clinical challenges in management of familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer. [10630179] Cancer 86(11 Suppl): 2533-9 (1999)
2009 10	Endometrial cancer and Lynch syndrome: clinical and pathologic considerations. [19078925] Cancer Control 16(1): 14-22 (2009)
2008 11	Feasibility of screening for Lynch syndrome among patients with colorectal cancer. [18809606] J Clin Oncol 26(35): 5783-8 (2008)
2008 12	Molecular, pathologic, and clinical features of early-onset endometrial cancer: identifying presumptive Lynch syndrome patients. [18310315] Clin Cancer Res 14(6): 1692-700 (2008)
2007 13	Toward a consensus in molecular diagnosis of hereditary nonpolyposis colorectal cancer (Lynch syndrome). [17312298] J Natl Cancer Inst 99(4): 261-3 (2007)
2004 14	Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability. [14970275] J Natl Cancer Inst 96(4): 261-8 (2004)
1996 15	Molecular mechanisms underlying hereditary nonpolyposis colorectal carcinoma. [8614002] J Natl Cancer Inst 88(5): 240-51 (1996)
2001 16	The selection for mismatch repair defects in hereditary nonpolyposis colorectal cancer: revising the mutator hypothesis. [11606363] Cancer Res 61(20): 7369-74 (2001)
2006 17	Phenotypic and genotypic heterogeneity in the Lynch syndrome: diagnostic, surveillance and management implications. [16479259] Eur J Hum Genet 14(4): 390-402 (2006)
2006 18	Recommendations for the care of individuals with an inherited predisposition to Lynch syndrome: a systematic review. [17003399] JAMA 296(12): 1507-17 (2006)
2006 19	Prediction of germline mutations and cancer risk in the Lynch syndrome. [17003396] JAMA 296(12): 1479-87 (2006)
2005 20	Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer). [15872200] N Engl J Med 352(18): 1851-60 (2005)
2007 21	Surveillance colonoscopy practice in Lynch syndrome in the Netherlands: A nationwide survey. [17729427] World J Gastroenterol 13(34): 4658-9 (2007)
2009 22	Diagnosis and management of hereditary colorectal cancer syndromes: Lynch syndrome as a model. [19654196] CMAJ 181(5): 273-80 (2009)
2010 23	Lessons from Lynch syndrome: a tumor biology-based approach to familial colorectal cancer. [20373868] Future Oncol 6(4): 539-49 (2010)
2010 24	Current hypotheses on how microsatellite instability leads to enhanced survival of Lynch Syndrome patients. [20631828] Clin Dev Immunol 2010(-): 170432 (2010)
2010 25	Application of molecular diagnostics for the detection of Lynch syndrome. [20629513] Expert Rev Mol Diagn 10(5): 651-65 (2010)
2010 26	On the advent of MSI testing of all colorectal cancers and a substantial part of other Lynch syndrome-related neoplasms. [20465492] Expert Rev Mol Diagn 10(4): 381-4 (2010)
2008 27	Carcinogenesis and microsatellite instability: the interrelationship between genetics and epigenetics. [17942460] Carcinogenesis 29(4): 673-80 (2008)
2010 28	A knockout for Lynch syndrome. [20102757] Gastroenterology 138(3): 820-2 (2010)
2008 29	Immunology and the Lynch syndrome. [18395102] Gastroenterology 134(4): 1246-9 (2008)
2008 30	The clinical phenotype of Lynch syndrome due to germ-line PMS2 mutations. [18602922] Gastroenterology 135(2): 419-28 (2008)
2009 31	Colorectal cancer risk perception on the basis of genetic test results in individuals at risk for Lynch syndrome. [19620492] J Clin Oncol 27(24): 3981-6 (2009)
2009 32	Mismatch repair genes in Lynch syndrome: a review. [19466295] Sao Paulo Med J 127(1): 46-51 (2009)
2003 33	Lynch syndrome: implications for the surgeon. [12952564] Clin Colorectal Cancer 3(2): 92-8 (2003)
2008 34	The risk of extra-colonic, extra-endometrial cancer in the Lynch syndrome. [18398828] Int J Cancer 123(2): 444-9 (2008)
2011 35	Prospective study of combined colon and endometrial cancer screening in women with lynch syndrome: a patient-centered approach. [21532810] J Oncol Pract 7(1): 43-7 (2011)
2010 36	Underdiagnosis of Lynch syndrome involves more than family history criteria. [20303416] Clin Gastroenterol Hepatol 8(6): 523-9 (2010)
2009 37	Current and emerging trends in Lynch syndrome identification in women with endometrial cancer. [19375789] Gynecol Oncol 114(1): 128-34 (2009)
2008 38	Clustering of Lynch syndrome malignancies with no evidence for a role of DNA mismatch repair. [18022218] Gynecol Oncol 108(2): 438-44 (2008)
2011 39	Hereditary prostate cancer as a feature of Lynch syndrome. [20872076] Fam Cancer 10(1): 37-42 (2011)
2008 40	The biochemical basis of microsatellite instability and abnormal immunohistochemistry and clinical behavior in Lynch syndrome: from bench to bedside. [17636426] Fam Cancer 7(1): 41-52 (2008)
2010 41	Current clinical criteria for Lynch syndrome are not sensitive enough to identify MSH6 mutation carriers. [20587412] J Med Genet 47(9): 579-85 (2010)
2007 42	Guidelines for the clinical management of Lynch syndrome (hereditary non-polyposis cancer). [17327285] J Med Genet 44(6): 353-62 (2007)
2009 43	Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications. [19659756] Clin Genet 76(1): 1-18 (2009)
2011 44	Evidence for classification of c.1852_1853AA>GC in MLH1 as a neutral variant for Lynch syndrome. [21247423] BMC Med Genet 12(-): 12 (2011)
2009 45	Recommendations from the EGAPP Working Group: genetic testing strategies in newly diagnosed individuals with colorectal cancer aimed at reducing morbidity and mortality from Lynch syndrome in relatives. [19125126] Genet Med 11(1): 35-41 (2009)
2009 46	EGAPP supplementary evidence review: DNA testing strategies aimed at reducing morbidity and mortality from Lynch syndrome. [19125127] Genet Med 11(1): 42-65 (2009)
PMC 47	Lynch syndrome from a surgeon perspective: retrospective study of clinical impact of mismatch repair protein expression analysis in colorectal cancer patients less than 50 years old. [24533633] BMC Surg 14():9 (2014)
PMC 48	Improving the quality of endoscopic surveillance of patients with lynch syndrome. [24719602] Gastroenterol Hepatol (N Y) 9(8):524-6 (2013)

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