NFKB

Dual roles of NF-kappaB in cell survival and implications of NF-kappaB inhibitors in neuroprotective therapy.
[18031598] Acta Pharmacol Sin 28(12): 1859-72 (2007)

Dissecting role of regulatory factors in NF-kappaB pathway with siRNA.
[15960883] Acta Pharmacol Sin 26(7): 780-8 (2005)

NF-kappaB family of transcription factors: central regulators of innate and adaptive immune functions.
[12097249] Clin Microbiol Rev 15(3): 414-29 (2002)

Recent advances in understanding NF-kappaB regulation.
[11979142] Inflamm Bowel Dis 8(3): 201-12 (2002)

Nuclear factor-kappaB: activation and regulation during toll-like receptor signaling.
[17349209] Cell Mol Immunol 4(1): 31-41 (2007)

Advances in NF-kappaB signaling transduction and transcription.
[16293211] Cell Mol Immunol 1(6): 425-35 (2004)

NF-kappaB and its regulation on the immune system.
[16285893] Cell Mol Immunol 1(5): 343-50 (2004)

Antigen-receptor signaling to nuclear factor kappa B.
[17098202] Immunity 25(5): 701-15 (2006)

Mechanistic aspects of NF-kappa B regulation: the emerging role of phosphorylation and proteolysis.
[7552992] Immunity 3(3): 263-72 (1995)

The IKK complex, a central regulator of NF-kappaB activation.
[20300203] Cold Spring Harb Perspect Biol 2(3): a000158 (2010)

Ubiquitination and degradation of the inhibitors of NF-kappaB.
[20182612] Cold Spring Harb Perspect Biol 2(2): a000166 (2010)

The nuclear factor-kappaB (NF-kappaB): from a versatile transcription factor to a ubiquitous therapeutic target.
[17068636] Acta Biochim Pol 53(4): 651-62 (2006)

The IkappaB kinase - a bridge between inflammation and cancer.
[18301380] Cell Res 18(3): 334-42 (2008)

Control of NF-kappa B transcriptional activation by signal induced proteolysis of I kappa B alpha.
[10582246] Philos Trans R Soc Lond B Biol Sci 354(1389): 1601-9 (1999)

The roles of the classical and alternative nuclear factor-kappaB pathways: potential implications for autoimmunity and rheumatoid arthritis.
[18771589] Arthritis Res Ther 10(4): 212 (2008)

The TRAF6-NF kappa B signaling pathway in autoimmunity: not just inflammation.
[15987501] Arthritis Res Ther 7(4): 170-3 (2005)

Fungal metabolites modulating NF-kappaB activity: an approach to cancer therapy and chemoprevention (review).
[18202775] Oncol Rep 19(2): 299-308 (2008)

Nuclear factor-kappaB in development, prevention, and therapy of cancer.
[17317814] Clin Cancer Res 13(4): 1076-82 (2007)

NF-kappaB activation in development and progression of cancer.
[17270016] Cancer Sci 98(3): 268-74 (2007)

Inhibition of tumor growth by NF-kappaB inhibitors.
[16925581] Cancer Sci 97(10): 990-5 (2006)

Nuclear factor-kappaB, an unappreciated tumor suppressor.
[18056430] Cancer Res 67(23): 11093-8 (2007)

How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex.
[10602462] Oncogene 18(49): 6867-74 (1999)

Activators and target genes of Rel/NF-kappaB transcription factors.
[10602461] Oncogene 18(49): 6853-66 (1999)

Regulation of DNA binding by Rel/NF-kappaB transcription factors: structural views.
[10602460] Oncogene 18(49): 6845-52 (1999)

NF-kappaB as a primary regulator of the stress response.
[10557108] Oncogene 18(45): 6163-71 (1999)

NF-kappaB signaling in lymphocytes: a new cast of characters.
[14657271] J Cell Sci 117(Pt 1): 31-9 (2004)

New insights into the role of nuclear factor-kappaB in cell growth regulation.
[11485895] Am J Pathol 159(2): 387-97 (2001)

Functions of NF-kappaB1 and NF-kappaB2 in immune cell biology.
[15214841] Biochem J 382(Pt 2): 393-409 (2004)

The inducible transcription factor NF-kappa B: structure-function relationship of its protein subunits.
[8452515] Biochem J 290 ( Pt 2)(-): 297-308 (1993)

A novel action of glucocorticoids--NF-kappa B inhibition.
[8761180] Br J Rheumatol 35(8): 709-10 (1996)

Dissection of the NF-kappaB signalling cascade in transgenic and knockout mice.
[16470223] Cell Death Differ 13(5): 861-72 (2006)

Signals from within: the DNA-damage-induced NF-kappaB response.
[16410802] Cell Death Differ 13(5): 773-84 (2006)

Nuclear factor-kappaB activation: from bench to bedside.
[18156302] Exp Biol Med (Maywood) 233(1): 21-31 (2008)

The NF-kappaB signalling pathway in human diseases: from incontinentia pigmenti to ectodermal dysplasias and immune-deficiency syndromes.
[12351572] Hum Mol Genet 11(20): 2371-5 (2002)

Negative regulation of nuclear factor-kappaB activation and function by glucocorticoids.
[11932204] J Mol Endocrinol 28(2): 69-78 (2002)

S-nitrosylation: physiological regulation of NF-kappaB.
[15187230] Proc Natl Acad Sci U S A 101(24): 8841-2 (2004)

Shared principles in NF-kappaB signaling.
[18267068] Cell 132(3): 344-62 (2008)

Missing pieces in the NF-kappaB puzzle.
[11983155] Cell 109 Suppl(-): S81-96 (2002)

IkappaB-NF-kappaB structures: at the interface of inflammation control.
[9865689] Cell 95(6): 729-31 (1998)

Tuning up inflammation: how DNA sequence and chromatin organization control the induction of inflammatory genes by NF-kappaB.
[16530189] FEBS Lett 580(12): 2843-9 (2006)

Alternative nuclear functions for NF-κB family members.
[21984965] Am J Cancer Res 1(4): 446-59 (2011)

Hypoxia. Regulation of NFkappaB signalling during inflammation: the role of hydroxylases.
[19291263] Arthritis Res Ther 11(1): 215 (2009)

Inhibiting NF-κB activation by small molecules as a therapeutic strategy.
[20493977] Biochim Biophys Acta 1799(10-12): 775-87 (2010)

COMMD proteins and the control of the NF kappa B pathway.
[17361106] Cell Cycle 6(6): 672-6 (2007)

NF-kappaB in renal inflammation.
[20651166] J Am Soc Nephrol 21(8): 1254-62 (2010)

NEMO nuances NF-kappaB.
[20056939] Circ Res 106(1): 10-2 (2010)

The nuclear factor-kappaB-interleukin-6 signalling pathway mediating vascular inflammation.
[20202975] Cardiovasc Res 86(2): 211-8 (2010)

NF-kappaB and the regulation of hematopoiesis.
[16528384] Cell Death Differ 13(5): 785-97 (2006)

NF-kappaB guides the survival and differentiation of developing lymphocytes.
[16528380] Cell Death Differ 13(5): 697-701 (2006)

NF-kappaB and IKK as therapeutic targets in cancer.
[16485028] Cell Death Differ 13(5): 738-47 (2006)

The NF-kappaB-mediated control of the JNK cascade in the antagonism of programmed cell death in health and disease.
[16456579] Cell Death Differ 13(5): 712-29 (2006)

Deciphering the pathway from the TCR to NF-kappaB.
[16439988] Cell Death Differ 13(5): 826-33 (2006)

Good cop, bad cop: the different faces of NF-kappaB.
[16410803] Cell Death Differ 13(5): 759-72 (2006)

Controlling NF-kappaB activation in T cells by costimulatory receptors.
[16410801] Cell Death Differ 13(5): 834-42 (2006)

Roles for NF-kappaB in nerve cell survival, plasticity, and disease.
[16397579] Cell Death Differ 13(5): 852-60 (2006)

NF-kappaB-related genetic diseases.
[16397577] Cell Death Differ 13(5): 843-51 (2006)

Reactive oxygen species mediate crosstalk between NF-kappaB and JNK.
[16341124] Cell Death Differ 13(5): 730-7 (2006)

PKCzeta at the crossroad of NF-kappaB and Jak1/Stat6 signaling pathways.
[16322752] Cell Death Differ 13(5): 702-11 (2006)

RIP1's function in NF-kappaB activation: from master actor to onlooker.
[20154702] Cell Death Differ 17(3): 379-80 (2010)

CYLD: a tumor suppressor deubiquitinase regulating NF-kappaB activation and diverse biological processes.
[19373246] Cell Death Differ 17(1): 25-34 (2010)

A20: central gatekeeper in inflammation and immunity.
[19008218] J Biol Chem 284(13): 8217-21 (2009)

Use of forward genetics to discover novel regulators of NF-kappaB.
[20516132] Cold Spring Harb Perspect Biol 2(6): a001966 (2010)

Signaling to NF-kappaB: regulation by ubiquitination.
[20300215] Cold Spring Harb Perspect Biol 2(3): a003350 (2010)

Selectivity of the NF-{kappa}B response.
[20452937] Cold Spring Harb Perspect Biol 2(4): a000257 (2010)

The regulatory logic of the NF-kappaB signaling system.
[20182598] Cold Spring Harb Perspect Biol 2(1): a000216 (2010)

Control of NF-kappaB-dependent transcriptional responses by chromatin organization.
[20066094] Cold Spring Harb Perspect Biol 1(4): a000224 (2009)

Specification of DNA binding activity of NF-kappaB proteins.
[20066093] Cold Spring Harb Perspect Biol 1(4): a000067 (2009)

The NF-kappaB family of transcription factors and its regulation.
[20066092] Cold Spring Harb Perspect Biol 1(4): a000034 (2009)

A structural guide to proteins of the NF-kappaB signaling module.
[20066103] Cold Spring Harb Perspect Biol 1(3): a000075 (2009)

Caspases leave the beaten track: caspase-mediated activation of NF-kappaB.
[16618810] J Cell Biol 173(2): 165-71 (2006)

Linear polyubiquitination: a new regulator of NF-kappaB activation.
[19543231] EMBO Rep 10(7): 706-13 (2009)

NF-kappaB activation pathways induced by T cell costimulation.
[14656980] FASEB J 17(15): 2187-93 (2003)

Beyond IkappaBs: alternative regulation of NF-kappaB activity.
[17431096] FASEB J 21(11): 2642-54 (2007)

Regulation of IkappaBalpha function and NF-kappaB signaling: AEBP1 is a novel proinflammatory mediator in macrophages.
[20396415] Mediators Inflamm 2010(-): 823821 (2010)

Ubiquitin in NF-kappaB signaling.
[19281271] Chem Rev 109(4): 1549-60 (2009)

NF-κB inducing kinase: a key regulator in the immune system and in cancer.
[20685151] Cytokine Growth Factor Rev 21(4): 213-26 (2010)

Crosstalk via the NF-kappaB signaling system.
[18515173] Cytokine Growth Factor Rev 19(3-4): 187-97 (2008)

Efficacy of dibenzoylmethane derivatives in protecting against endoplasmic reticulum stress and inhibiting nuclear factor kappa B on dextran sulfate sodium induced colitis in mice.
[21139246] Biol Pharm Bull 33(12): 2029-32 (2010)

Cardiomyocyte NF-kappaB p65 promotes adverse remodelling, apoptosis, and endoplasmic reticulum stress in heart failure.
[20797985] Cardiovasc Res 89(1): 129-38 (2011)

Inhibition of apoptosis by Nur77 through NF-kappaB activity modulation.
[16082387] Cell Death Differ 13(2): 293-300 (2006)

Gemcitabine/cannabinoid combination triggers autophagy in pancreatic cancer cells through a ROS-mediated mechanism.
[21525939] Cell Death Dis 2(): e152 (2011)

Multiple facets of NF-kappaB in the heart: to be or not to NF-kappaB.
[21527742] Circ Res 108(9): 1122-32 (2011)

A noncanonical Flt3ITD/NF-kappaB signaling pathway represses DAPK1 in acute myeloid leukemia.
[22096027] Clin Cancer Res 18(2): 360-9 (2012)

Forkhead transcription factors (FoxOs) promote apoptosis of insulin-resistant macrophages during cholesterol-induced endoplasmic reticulum stress.
[18728232] Diabetes 57(11): 2967-76 (2008)

Posttranslational modifications of NF-kappaB: another layer of regulation for NF-kappaB signaling pathway.
[20363318] Cell Signal 22(9): 1282-90 (2010)

Malt1 and cIAP2-Malt1 as effectors of NF-kappaB activation: kissing cousins or distant relatives?
[19772915] Cell Signal 22(1): 9-22 (2010)

The NF-kappaB activation pathways, emerging molecular targets for cancer prevention and therapy.
[20001209] Expert Opin Ther Targets 14(1): 45-55 (2010)

NF-kappaB in carcinoma therapy and prevention.
[18694378] Expert Opin Ther Targets 12(9): 1109-22 (2008)

Focus on molecules: nuclear factor-kappaB.
[18472097] Exp Eye Res 88(1): 2-3 (2009)

NF-kappaB signaling: multiple angles to target OA.
[20199390] Curr Drug Targets 11(5): 599-613 (2010)

A Retrospective on Nuclear Receptor Regulation of Inflammation: Lessons from GR and PPARs.
[21941526] PPAR Res 2011(-): 742785 (2011)

Molecular mechanisms of system control of NF-kappaB signaling by IkappaBalpha.
[20055496] Biochemistry 49(8): 1560-7 (2010)

NF-κB addiction and its role in cancer: 'one size does not fit all'.
[21170083] Oncogene 30(14): 1615-30 (2011)

Nuclear factor-kappaB activation: a question of life or death.
[16248967] J Biochem Mol Biol 35(1): 28-40 (2002)

MicroRNAs in NF-kappaB signaling.
[21502305] J Mol Cell Biol 3(3): 159-66 (2011)

AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan.
[21431325] J Mol Med (Berl) 89(7): 667-76 (2011)

The IkappaB kinase complex: master regulator of NF-kappaB signaling.
[18626576] Immunol Res 42(1-3): 3-18 (2008)

Structural studies of NF-κB signaling.
[21135870] Cell Res 21(1): 183-95 (2011)

Deubiquitinases in the regulation of NF-κB signaling.
[21119682] Cell Res 21(1): 22-39 (2011)

The nuclear signaling of NF-kappaB: current knowledge, new insights, and future perspectives.
[19997086] Cell Res 20(1): 24-33 (2010)

NF-kappaB and cancer: how intimate is this relationship.
[19823771] Mol Cell Biochem 336(1-2): 25-37 (2010)

NF-kappaB signaling pathways regulated by CARMA family of scaffold proteins.
[21187856] Cell Res 21(1): 55-70 (2011)

Nuclear initiated NF-kappaB signaling: NEMO and ATM take center stage.
[21187855] Cell Res 21(1): 116-30 (2011)

Non-canonical NF-kappaB signaling pathway.
[21173796] Cell Res 21(1): 71-85 (2011)

NF-kappaB in the regulation of epithelial homeostasis and inflammation.
[21151201] Cell Res 21(1): 146-58 (2011)

Expanding role of ubiquitination in NF-kappaB signaling.
[21135871] Cell Res 21(1): 6-21 (2011)

CARMA3: A novel scaffold protein in regulation of NF-kappaB activation and diseases.
[21537470] World J Biol Chem 1(12): 353-61 (2010)

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