Nrf2

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Nrf2

LE WE PMID CA

Nrf2

2017

Nrf2

Allergy (Contact eczema)

ARE (Antioxidant responsive element)

beta cell (Pancreas)

Cell stress (Electrophilic)

Chemoprevention

COPD

ERS UFR (Diseases)

Glutamate cysteine ligase

Glutathione synthase

Glutathione

GSK3

Heme oxygenase

Keap1

NADPH quinone oxidoreductase

NQO1 NAD(P)H quinone acceptor oxidoreductase1

Nrf1

Nrf2

Proteasome (BASKET)

PSMB6

Redox (BASKET)

Resveratrol

Sulfiredoxin

Sulforaphane

Xenobiotics

2007 1	Activation of endothelial nitric oxide synthase by dietary isoflavones: role of NO in Nrf2-mediated antioxidant gene expression. [17498676] Cardiovasc Res 75(2): 261-74 (2007)
2009 2	Role of Nrf2-mediated heme oxygenase-1 upregulation in adaptive survival response to nitrosative stress. [19727608] Arch Pharm Res 32(8): 1163-76 (2009)
2004 3	A strategy for cancer prevention: stimulation of the Nrf2-ARE signaling pathway. [15252150] Mol Cancer Ther 3(7): 885-93 (2004)
2004 4	Nrf2-dependent gene expressions: a molecular toxicological aspect. [15206576] J Toxicol Sci 29(2): 81-9 (2004)
2010 5	Endothelial Nrf2 activation: a new target for resveratrol? [20472762] Am J Physiol Heart Circ Physiol 299(1): H10-2 (2010)
2007 6	Roles and mechanisms of action of the Nrf2 transcription factor in skin morphogenesis, wound repair and skin cancer. [17380153] Cell Death Differ 14(7): 1250-4 (2007)
2009 7	The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress. [19182219] J Biol Chem 284(20): 13291-5 (2009)
2008 8	The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodegeneration. [19076431] Ann N Y Acad Sci 1147(-): 61-9 (2008)
2009 9	Transcriptional regulation of the AP-1 and Nrf2 target gene sulfiredoxin. [19326073] Mol Cells 27(3): 279-82 (2009)
2009 10	The Nrf2/ARE pathway as a potential therapeutic target in neurodegenerative disease. [18717629] Antioxid Redox Signal 11(3): 497-508 (2009)
2010 11	Nrf2 and PPAR{gamma}: PPARtnering against oxidant-induced lung injury. [20634499] Am J Respir Crit Care Med 182(2): 134-5 (2010)
2010 12	Possible involvement of granulocyte oxidative burst in Nrf2 signaling in cancer. [20516531] Indian J Med Res 131(-): 609-16 (2010)
2010 13	Nrf2: friend or foe for chemoprevention? [19793802] Carcinogenesis 31(1): 90-9 (2010)
2010 14	NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector. [20361926] Arch Biochem Biophys 501(1): 116-23 (2010)
2009 15	Heightened endoplasmic reticulum stress in the lungs of patients with chronic obstructive pulmonary disease: the role of Nrf2-regulated proteasomal activity. [19797762] Am J Respir Crit Care Med 180(12): 1196-207 (2009)
2009 16	Nrf2:INrf2 (Keap1) signaling in oxidative stress. [19666107] Free Radic Biol Med 47(9): 1304-9 (2009)
2008 17	Dual roles of Nrf2 in cancer. [18838122] Pharmacol Res 58(5-6): 262-70 (2008)
2011 18	The role of the antioxidant and longevity-promoting Nrf2 pathway in metabolic regulation. [21102319] Curr Opin Clin Nutr Metab Care 14(1): 41-8 (2011)
2007 19	Nrf2/ARE regulated antioxidant gene expression in endothelial and smooth muscle cells in oxidative stress: implications for atherosclerosis and preeclampsia. [17437032] Sheng Li Xue Bao 59(2): 117-27 (2007)
2011 20	Targeting Glycogen Synthase Kinase-3β for Therapeutic Benefit against Oxidative Stress in Alzheimer's Disease: Involvement of the Nrf2-ARE Pathway. [21629716] Int J Alzheimers Dis 2011(-): 985085 (2011)
2008 21	Nrf2 signaling: an adaptive response pathway for protection against environmental toxic insults. [18164232] Mutat Res 659(1-2): 31-9 (2008)
2004 22	An important role of Nrf2-ARE pathway in the cellular defense mechanism. [15469687] J Biochem Mol Biol 37(2): 139-43 (2004)
2009 23	Regulation of glutathione synthesis. [18601945] Mol Aspects Med 30(1-2): 42-59 (2009)
2010 24	The Nrf2-Keap1-ARE toxicity pathway as a cellular sensor for skin sensitizers--functional relevance and a hypothesis on innate reactions to skin sensitizers. [19767620] Toxicol Sci 113(2): 284-92 (2010)
2010 25	Nrf2 in toxicology and pharmacology: the good, the bad and the ugly? [20079756] Toxicol Appl Pharmacol 244(1): 1-3 (2010)
2010 26	Nrf2 the rescue: effects of the antioxidative/electrophilic response on the liver. [20122946] Toxicol Appl Pharmacol 244(1): 57-65 (2010)
2010 27	ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function. [19501608] Toxicol Appl Pharmacol 244(1): 77-83 (2010)
2010 28	Nrf2 signaling and cell survival. [19538984] Toxicol Appl Pharmacol 244(1): 37-42 (2010)
2010 29	Cysteine-based regulation of the CUL3 adaptor protein Keap1. [19560482] Toxicol Appl Pharmacol 244(1): 21-6 (2010)
2010 30	A systems biology perspective on Nrf2-mediated antioxidant response. [19716833] Toxicol Appl Pharmacol 244(1): 84-97 (2010)
2008 31	Dithiolethiones for cancer chemoprevention: where do we stand? [19001432] Mol Cancer Ther 7(11): 3470-9 (2008)
2009 32	Molecular mechanisms of Nrf2-mediated antioxidant response. [18618599] Mol Carcinog 48(2): 91-104 (2009)
2010 33	Regulation of the Nrf2-Keap1 antioxidant response by the ubiquitin proteasome system: an insight into cullin-ring ubiquitin ligases. [20486766] Antioxid Redox Signal 13(11): 1699-712 (2010)
2010 34	Regulation of NF-E2-related factor 2 signaling for cancer chemoprevention: antioxidant coupled with antiinflammatory. [20486765] Antioxid Redox Signal 13(11): 1679-98 (2010)
2010 35	Chemistry of the cysteine sensors in Kelch-like ECH-associated protein 1. [20486763] Antioxid Redox Signal 13(11): 1749-61 (2010)
2010 36	When NRF2 talks, who's listening? [20367496] Antioxid Redox Signal 13(11): 1649-63 (2010)

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