Oxygen (Hypoxia)

The ubiquitin ligase Siah2 and the hypoxia response.
[19372575] Mol Cancer Res 7(4): 443-51 (2009)

"Translating" tumor hypoxia: unfolded protein response (UPR)-dependent and UPR-independent pathways.
[16849518] Mol Cancer Res 4(7): 423-36 (2006)

Molecular aspects of tumour hypoxia.
[19383328] Mol Oncol 2(1): 41-53 (2008)

How do red blood cells cause hypoxic vasodilation? The SNO-hemoglobin paradigm.
[16751292] Am J Physiol Heart Circ Physiol 291(4): H1507-12 (2006)

The effects of hypoxia on the cells of the pulmonary vasculature.
[17666559] Eur Respir J 30(2): 364-72 (2007)

Imaging findings in neonatal hypoxia: a practical review.
[19098177] AJR Am J Roentgenol 192(1): 41-7 (2009)

Second generation hypoxia imaging agents.
[8441031] J Nucl Med 34(3): 411-3 (1993)

Antioxidant enzyme gene transfer for ischemic diseases.
[19233238] Adv Drug Deliv Rev 61(4): 351-63 (2009)

Perinatal hypoxic-ischemic encephalopathy.
[21197402] J Biomed Biotechnol 2011(-): 609813 (2011)

Nitric oxide, cytochrome C oxidase, and the cellular response to hypoxia.
[19713530] Arterioscler Thromb Vasc Biol 30(4): 643-7 (2010)

Regulation of hypoxia-inducible genes by PGC-1 alpha.
[19948845] Arterioscler Thromb Vasc Biol 30(4): 662-6 (2010)

Applications of nitroimidazole in vivo hypoxia imaging in ischemic stroke.
[18369176] Stroke 39(5): 1629-37 (2008)

Pathophysiological response to hypoxia - from the molecular mechanisms of malady to drug discovery: drug discovery for targeting the tumor microenvironment.
[21422725] J Pharmacol Sci 115(4): 446-52 (2011)

Pathophysiological response to hypoxia - from the molecular mechanisms of malady to drug discovery:hypoxia-inducible factor-1 (HIF-1)-active cells as a target for cancer therapy.
[21422727] J Pharmacol Sci 115(4): 440-5 (2011)

Pathophysiological response to hypoxia - from the molecular mechanisms of malady to drug discovery: epigenetic regulation of the hypoxic response via hypoxia-inducible factor and histone modifying enzymes.
[21422728] J Pharmacol Sci 115(4): 453-8 (2011)

Mitochondrial reactive oxygen species regulate hypoxic signaling.
[19781926] Curr Opin Cell Biol 21(6): 894-9 (2009)

Low oxygen stimulates the intellect. Symposium on hypoxia and development, physiology and disease.
[16799463] EMBO Rep 7(7): 679-84 (2006)

Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression.
[12153983] FASEB J 16(10): 1151-62 (2002)

NLCQ-1 (NSC 709257): exploiting hypoxia with a weak DNA-intercalating bioreductive drug.
[14654556] Clin Cancer Res 9(15): 5714-20 (2003)

ROS-dependent signaling mechanisms for hypoxic Ca(2+) responses in pulmonary artery myocytes.
[19764882] Antioxid Redox Signal 12(5): 611-23 (2010)

Oxidant and redox signaling in vascular oxygen sensing: implications for systemic and pulmonary hypertension.
[18315496] Antioxid Redox Signal 10(6): 1137-52 (2008)

Red blood cells (RBCs), epoxyeicosatrienoic acids (EETs) and adenosine triphosphate (ATP).
[20631410] Pharmacol Rep 62(3): 468-74 (2010)

Systemic, cellular and molecular analysis of chemoreflex-mediated sympathoexcitation by chronic intermittent hypoxia.
[17124274] Exp Physiol 92(1): 39-44 (2007)

Prolyl 4-hydroxylase activity-responsive transcription factors: from hydroxylation to gene expression and neuroprotection.
[17981760] Front Biosci 13(-): 2875-87 (2008)

Upregulation of osmo-mechanosensitive TRPV4 channel facilitates chronic hypoxia-induced myogenic tone and pulmonary hypertension.
[22207590] Am J Physiol Lung Cell Mol Physiol 302(6): L555-68 (2012)

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