SIRT1

The critical role of the class III histone deacetylase SIRT1 in cancer.
[19244112] Cancer Res 69(5): 1702-5 (2009)

Bursting and calcium oscillations in pancreatic beta-cells: specific pacemakers for specific mechanisms.
[20628025] Am J Physiol Endocrinol Metab 299(4): E517-32 (2010)

SIRT1 and p53, effect on cancer, senescence and beyond.
[20471503] Biochim Biophys Acta 1804(8): 1684-9 (2010)

Nutrient-dependent regulation of PGC-1alpha's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5.
[20005308] Biochim Biophys Acta 1804(8): 1676-83 (2010)

Biochemical effects of SIRT1 activators.
[19897059] Biochim Biophys Acta 1804(8): 1626-34 (2010)

SIRT1-dependent regulation of chromatin and transcription: linking NAD(+) metabolism and signaling to the control of cellular functions.
[19879981] Biochim Biophys Acta 1804(8): 1666-75 (2010)

SIRT1: linking adaptive cellular responses to aging-associated changes in organismal physiology.
[17119153] Physiology (Bethesda) 21(-): 404-10 (2006)

NO targets SIRT1: a novel signaling network in endothelial senescence.
[18716320] Arterioscler Thromb Vasc Biol 28(9): 1577-9 (2008)

Activating SIRT1: a new strategy to prevent atherosclerosis?
[18784217] Cardiovasc Res 80(2): 163-4 (2008)

Roles of FoxO1 and Sirt1 in the central regulation of food intake.
[21048357] Endocr J 57(11): 939-46 (2010)

Transcriptional regulation of neuronal genes and its effect on neural functions: NAD-dependent histone deacetylase SIRT1 (Sir2alpha).
[16006743] J Pharmacol Sci 98(3): 200-4 (2005)

SIRT1 controls circadian clock circuitry and promotes cell survival: a connection with age-related neoplasms.
[19439501] FASEB J 23(9): 2803-9 (2009)

Targeting Forkhead box O1 from the concept to metabolic diseases: lessons from mouse models.
[20615072] Antioxid Redox Signal 14(4): 649-61 (2011)

Therapeutic potential of SIRT1 and NAMPT-mediated NAD biosynthesis in type 2 diabetes.
[19273250] Front Biosci 14(-): 2983-95 (2009)

Adiponectin: a key adipokine in alcoholic fatty liver.
[19491377] Exp Biol Med (Maywood) 234(8): 850-9 (2009)

Regulation of SIRT1 in cellular functions: role of polyphenols.
[20450879] Arch Biochem Biophys 501(1): 79-90 (2010)

Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation.
[19356714] Cell Metab 9(4): 327-38 (2009)

SirT1 regulates adipose tissue inflammation.
[22110092] Diabetes 60(12): 3235-45 (2011)

SIRT1/eNOS axis as a potential target against vascular senescence, dysfunction and atherosclerosis.
[20215708] J Atheroscler Thromb 17(5): 431-5 (2010)

SIRT1 genetic variation is related to BMI and risk of obesity.
[19741164] Diabetes 58(12): 2828-34 (2009)

Sirtuin 1 in lipid metabolism and obesity.
[21345154] Ann Med 43(3): 198-211 (2011)

AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan.
[21431325] J Mol Med (Berl) 89(7): 667-76 (2011)

Mammalian Sirt1: insights on its biological functions.
[21549004] Cell Commun Signal 9(-): 11 (2011)

The NAD World: a new systemic regulatory network for metabolism and aging--Sirt1, systemic NAD biosynthesis, and their importance.
[19130305] Cell Biochem Biophys 53(2): 65-74 (2009)

SIRT1 and AMPK in regulating mammalian senescence: a critical review and a working model.
[21130086] FEBS Lett 585(7): 986-94 (2011)

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