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TSC1 Hamartin
LE WE PMID CA
TSC1 Hamartin3321TSC1 Hamartin

AMP activated protein kinase

Cell polarity

LKB1

Lymphangioleiomyomatosis

MTOR

mTORC1

Neuron (Axon)

P53

PI3K

Pmel17

RHEB

SAD

TSC1 Hamartin

TSC2 Tuberin

Tuberous sclerosis

2004  
1
A patient with TSC1 germline mutation whose clinical phenotype was limited to lymphangioleiomyomatosis.
[15257730] J Intern Med 256(2): 166-73 (2004)
2007  
2
All roads lead to mTOR: integrating inflammation and tumor angiogenesis.
[18073529] Cell Cycle 6(24): 3011-4 (2007)
2006  
3
AMPK and cell proliferation--AMPK as a therapeutic target for atherosclerosis and cancer.
[16613876] J Physiol 574(Pt 1): 63-71 (2006)
2010  
4
2008  
5
The TSC1-TSC2 complex: a molecular switchboard controlling cell growth.
[18466115] Biochem J 412(2): 179-90 (2008)
2008  
6
The Tsc1-Tsc2 complex influences neuronal polarity by modulating TORC1 activity and SAD levels.
[18794342] Genes Dev 22(18): 2447-53 (2008)
2007  
7
Molecular pathogenesis of lymphangioleiomyomatosis: lessons learned from orphans.
[17099139] Am J Respir Cell Mol Biol 36(4): 398-408 (2007)
2010  
8
The role of chemokines in migration of metastatic-like lymphangioleiomyomatosis cells.
[20666708] Crit Rev Immunol 30(4): 387-94 (2010)
2009  
9
A complex interplay between Akt, TSC2 and the two mTOR complexes.
[19143635] Biochem Soc Trans 37(Pt 1): 217-22 (2009)

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