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Cutaneous signs of selected systemic diseases Kihiczak NI; Leevy CB; Krysicki MM; Janniger CK; Schneider I; Shriner DL; Lambert WC; Schwartz RAJ Med 1999[]; 30 (1-2): 3-12In this work we will discuss three cutaneous markers of systemic disease. Acanthosis nigricans is the most widely known in this category. Cutaneous angiokeratomas are usually associated with enzyme defect disorders, such as Fabry's disease, and are linked in this work as a reactive pattern in hepatorenal failure. Mast cell disease may occur in a number of forms, often with systemic involvement.|Acanthosis Nigricans/diagnosis/etiology[MESH]|Angiokeratoma/diagnosis/etiology[MESH]|Humans[MESH]|Liver Failure/*complications[MESH]|Mastocytosis/diagnosis/etiology[MESH]|Renal Insufficiency/*complications[MESH]|Skin Diseases/diagnosis/*etiology[MESH]|Skin Neoplasms/etiology[MESH] |
