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l�ll Dihydropyrimidine dehydrogenase: its role in 5-fluorouracil clinical toxicity and tumor resistance Diasio RB; Johnson MRClin Cancer Res 1999[Oct]; 5 (10): 2672-3�|Antimetabolites, Antineoplastic/*adverse effects[MESH]|Dihydrouracil Dehydrogenase (NADP)[MESH]|Drug Resistance, Neoplasm[MESH]|Fluorouracil/*adverse effects[MESH]|Humans[MESH]|Neoplasms/*drug therapy/enzymology[MESH]|Oxidoreductases/*physiology[MESH] |