Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
Allosteric drugs: thinking outside the active-site box DeDecker BSChem Biol 2000[May]; 7 (5): R103-7Recently, a class of small molecules that thermally stabilize the tumor suppressor p53 was selected from a small-molecule library. This, and other recent work, demonstrates the feasibility of taking a lead from nature and selecting new classes of drugs that function by allosteric mechanisms.|Allosteric Regulation[MESH]|Binding Sites[MESH]|Humans[MESH]|Nitric Oxide Synthase Type II[MESH]|Nitric Oxide Synthase/metabolism[MESH]|Peptide Library[MESH]|Protein Engineering/methods[MESH]|Tumor Suppressor Protein p53/*chemistry/genetics/*metabolism[MESH] |
