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lüll The science of bonding: from first to sixth generation Kugel G; Ferrari MJ Am Dent Assoc 2000[Jun]; 131 Suppl (ä): 20S-25SBACKGROUND: Adhesive dentistry has revolutionized restorative dental practice during the past 30 years. Improved adhesive materials have made resin-based composite restorations more reliable and long-standing. CLINICAL IMPLICATIONS: This article reviews the evolution of bonding from the first generation to current bonding materials. It discusses the composition and effectiveness of the various iterations. Current products are highlighted to improve clinical use and performance of the materials.|Adhesives/chemistry/*classification[MESH]|Composite Resins/chemistry/classification[MESH]|Dental Bonding/*classification/methods[MESH]|Dental Enamel/ultrastructure[MESH]|Dental Materials/chemistry/*classification[MESH]|Dental Restoration, Permanent/methods[MESH]|Dentin-Bonding Agents/chemistry/classification[MESH]|Humans[MESH] |