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The craniofacial dysostosis syndromes: current surgical thinking and future directions Posnick JC; Ruiz RLCleft Palate Craniofac J 2000[Sep]; 37 (5): 433Craniofacial dysostosis is the term applied to familial forms of craniosynostosis in which the sutural involvement generally includes the cranial vault, cranial base, and midfacial skeletal structures. The syndromic forms of craniofacial dysostosis were initially described by Carpenter, Apert, Crouzon, Saethre and Chotzen, Pfeiffer, and others. In addition to the dysmorphic cranial features, affected individuals may have profound alterations in facial skeletal development. Surgical reconstruction requires thoughtfully sequenced and staged procedures with consideration for the individual's specific malformations, craniofacial growth patterns, and psychosocial needs. Management of the craniofacial dysostosis syndromes is surgical, but the indications and the timing, type, and effectiveness of each stage of reconstruction have not been well evaluated and remains as much an art as a science. This article reviews the specific characteristic clinical features of the craniofacial dysostosis syndromes and presents current philosophy and rationale for the staging of reconstruction.|Craniofacial Dysostosis/*surgery[MESH]|Humans[MESH]|Maxillofacial Development[MESH]|Oral Surgical Procedures/trends[MESH]|Patient Care Planning[MESH]|Plastic Surgery Procedures/trends[MESH]|Time Factors[MESH] |
