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Disruption and infection of median sternotomy: a comprehensive review Losanoff JE; Richman BW; Jones JWEur J Cardiothorac Surg 2002[May]; 21 (5): 831-9Disruption and infection of median sternotomy wounds are grave complications often associated with prolonged hospitalization, high cost, and significant mortality. Effective prevention techniques are still debated. Successful management requires early recognition based on a high index of suspicion, detailed physical examination, appreciation of the clinical signs and symptoms, timely imaging studies, and prompt surgical therapy. Improvements in perioperative management and critical care of patients with multisystem organ failure can reduce morbidity and mortality rates. Sternal salvage and direct sternal reclosure are possible when the infection is diagnosed early. Techniques utilizing lateral sternal support should be first-line options in the condition. Muscle flap techniques should be the next consideration when direct closure has failed or cannot be attempted.|*Surgical Wound Infection/diagnosis/drug therapy/prevention & control[MESH]|Anti-Bacterial Agents/therapeutic use[MESH]|Humans[MESH]|Mediastinitis/surgery[MESH]|Risk Factors[MESH]|Sternum/*surgery[MESH]|Surgical Wound Dehiscence/diagnosis/therapy[MESH]|Suture Techniques[MESH] |
