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Disease laterality, eye dominance, and visual handicap in patients with unilateral full thickness macular holes Waheed K; Laidlaw DABr J Ophthalmol 2003[May]; 87 (5): 626-8AIM: To investigate the association between visual handicap, laterality, and historical eye dominance in patients presenting with unilateral full thickness macular holes (FTMH). METHODS: Consecutive patients presenting with unilateral FTMH and no other visually significant ocular pathology including abnormalities of binocular vision were included. A questionnaire and case note review were performed to determine the mode of presentation, presence of symptomatic binocular interference, historically dominant eye, and whether they elected to undergo surgery. RESULTS: 44 eyes of 44 patients fulfilled the inclusion criteria. 21 (48%) affected eyes were right sided and 56% of FTMH were in the historically dominant eye. 76% of FTMH in historically dominant eyes presented symptomatically compared to 36% in non-dominant eyes (p= 0.003). 72% of patients with FTMH affecting their historically dominant eye were aware of binocular interference in day to day binocular viewing compared with 21% when the FTMH was in the non-dominant eye (p= 0.001). 23 (52%) patients elected to undergo surgery, of whom 18/23(78%) had FTMH in their historically dominant eye (p= 0.0003). CONCLUSION: This study suggests that eye dominance may be an important determinant of the visual handicap suffered by patients with unilateral FTMH.|Aged[MESH]|Aged, 80 and over[MESH]|Dominance, Ocular/*physiology[MESH]|Female[MESH]|Humans[MESH]|Male[MESH]|Middle Aged[MESH]|Retinal Perforations/*physiopathology/surgery[MESH]|Surveys and Questionnaires[MESH]|Vision Disorders/*physiopathology[MESH]|Vision, Binocular/physiology[MESH]|Visual Acuity/physiology[MESH] |