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Monitoring von Tienopyridinen und GPIIb/IIIa-Antagonisten: Einfache, praktikable Plattchenfunktionstests Halbmayer WMHamostaseologie 2004[Aug]; 24 (3): 203-6Platelet function analyses were known as mystified, complicated, and time consuming laboratory investigations with a high coefficient of variation. Only in rare cases they led to precise interpretations under routine clinical laboratory conditions. In the first line they were focussed on bleeding tendencies. Only few were suited to evaluate the state of hyperaggregability of platelets. This short presentation of the GTH-Symposium 2004 gives a survey on the most simple and practicable tests for checking platelet function which may be used for the monitoring of therapy with tienopyridines and glycoprotein IIb/IIIa-receptor antagonists.|Blood Platelets/cytology/drug effects/physiology[MESH]|Drug Monitoring/methods[MESH]|Humans[MESH]|Platelet Aggregation Inhibitors/pharmacokinetics/pharmacology/*therapeutic use[MESH]|Platelet Aggregation/drug effects/physiology[MESH]|Platelet Function Tests[MESH]|Platelet Glycoprotein GPIIb-IIIa Complex/*antagonists & inhibitors/drug effects/*physiology[MESH]|Pyridines/pharmacokinetics/pharmacology/*therapeutic use[MESH]|Thiophenes/pharmacokinetics/pharmacology/*therapeutic use[MESH] |
