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Phosphoinositides: older than we first thought?Cooke FTCurr Biol 2004[Sep]; 14 (18): R762-4Despite nearly 50 years of study, it is good to see that phosphoinositides are still capable of springing the odd surprise. Signaling by the second messenger phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P(3)) was thought to be absent in yeast, but a recent paper now describes the presence of PtdIns(3,4,5)P(3) in Schizosaccharomyces pombe.|*Second Messenger Systems[MESH]|*Signal Transduction[MESH]|Evolution, Molecular[MESH]|Models, Biological[MESH]|Phosphatidylinositol Phosphates/*metabolism[MESH]|Schizosaccharomyces/*metabolism/physiology[MESH]|Species Specificity[MESH] |
