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Shifted from Wnt to Hedgehog signaling pathways Han C; Lin XMol Cell 2005[Feb]; 17 (3): 321-2Two papers in recent issue of Developmental Cell (Glise et al. 2005; Gorfinkiel et al. 2005) have shown that Shifted, a Drosophila ortholog of Wnt Inhibitory Factor (WIF), modulates the distribution of Hedgehog protein in the wing imaginal disc through a Wnt-independent mechanism.|Adaptor Proteins, Signal Transducing[MESH]|Animals[MESH]|Carrier Proteins/chemistry/genetics/physiology[MESH]|Drosophila Proteins/chemistry/genetics/*physiology[MESH]|Drosophila/genetics/growth & development/physiology[MESH]|Genes, Insect[MESH]|Hedgehog Proteins[MESH]|Humans[MESH]|Intercellular Signaling Peptides and Proteins/genetics/*physiology[MESH]|Mutation[MESH]|Repressor Proteins/chemistry/genetics/physiology[MESH]|Signal Transduction[MESH]|Wings, Animal/growth & development[MESH]|Wnt Proteins[MESH] |
