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English Wikipedia
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New developments in the endoscopic surveillance of Barrett s oesophagus Bergman JJ; Tytgat GNGut 2005[Mar]; 54 Suppl 1 (Suppl 1): i38-42Patients with a Barrett's oesophagus are at risk for developing an adenocarcinoma of the distal oesophagus. Therefore, many patients undergo endoscopic surveillance to detect dysplasia and/or cancer at an early and curable stage. However, early neoplastic lesions are difficult to identify with standard endoscopy. In addition, the low incidence of these lesions, currently estimated at 0.5% per year, reduces the cost effectiveness of the surveillance strategy. New developments, aimed at improving the efficacy of Barrett's surveillance, focus on two areas: 1) improvement of the endoscopic detection of early neoplastic lesions; and 2) the use of alternative techniques for tissue sampling combined with molecular markers to identify patients at risk for malignant degeneration.|Adenocarcinoma/*diagnosis/pathology[MESH]|Barrett Esophagus/*diagnosis/pathology[MESH]|Biomarkers/analysis[MESH]|Esophageal Neoplasms/*diagnosis/pathology[MESH]|Esophagoscopy/*methods[MESH]|Esophagus/pathology[MESH]|Humans[MESH]|In Situ Hybridization, Fluorescence/methods[MESH]|Precancerous Conditions/*diagnosis/pathology[MESH] |
