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Neurotransmission: emerging roles of endocannabinoids Kreitzer ACCurr Biol 2005[Jul]; 15 (14): R549-51Postsynaptic release of endocannabinoids can inhibit presynaptic neurotransmitter release on short and long timescales. This retrograde inhibition occurs at both excitatory and inhibitory synapses and may provide a mechanism for synaptic gain control, short-term associative plasticity, reduction of synaptic crosstalk, and metaplasticity.|*Endocannabinoids[MESH]|Brain/*metabolism[MESH]|Calcium/metabolism[MESH]|Cannabinoid Receptor Modulators/*metabolism[MESH]|Humans[MESH]|Neural Inhibition/*physiology[MESH]|Neurotransmitter Agents/*physiology[MESH]|Signal Transduction/*physiology[MESH]|Synapses/metabolism/*physiology[MESH]|Synaptic Transmission/*physiology[MESH] |
