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l�ll Resection of colorectal liver metastases: current perspectives McLoughlin JM; Jensen EH; Malafa MCancer Control 2006[Jan]; 13 (1): 32-41BACKGROUND: Metastases to the liver is the leading cause of death in patients with colorectal cancer. METHODS: The authors review the data on diagnosis and management of this clinical problem, and they discuss management options that can be considered. RESULTS: Complete surgical resection of metastases from colorectal cancer that are localized to the liver results in 5-year survival rates ranging from 26% to 40%. CONCLUSIONS: By adding modalities such as targeted systemic therapy and other "local" treatments for liver metastases, further gains in survival are anticipated.|Colorectal Neoplasms/*pathology[MESH]|Humans[MESH]|Liver Neoplasms/mortality/*secondary/*surgery[MESH]|Neoadjuvant Therapy[MESH]|Patient Selection[MESH]|Survival Analysis[MESH]|Tomography, X-Ray Computed[MESH]|Treatment Outcome[MESH] |