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Hepatocellular carcinoma An overview Motola-Kuba D; Zamora-Valdes D; Uribe M; Mendez-Sanchez NAnn Hepatol 2006[Jan]; 5 (1): 16-24Hepatocellular carcinoma is a common malignancy affecting approximately one million people around the world every year. The incidence is low in the occidental world and high in locations such as Southeast Asia and sub-Saharan Africa. Hepatocellular carcinoma primarily affects old people, reaching its highest prevalence among those aged 65 to 69 years old. Chronic infection by the hepatitis B virus is the most common cause of this disease. Other important causes are cirrhosis, chronic viral hepatitis (hepatitis C virus, and hepatitis B plus D viruses), alcohol abuse, obesity, hemochromatosis, alfa1-antitripsin deficiency, and toxins similar to aflatoxin. In most cases, hepatocellular carcinoma is asymptomatic and has a low life expectancy. This article presents a review of the most important epidemiological, diagnostic and treatment data about this disease.|Age Distribution[MESH]|Aged[MESH]|Biopsy, Needle[MESH]|Carcinoma, Hepatocellular/*diagnosis/*epidemiology/surgery[MESH]|Causality[MESH]|Female[MESH]|Hepatectomy/methods[MESH]|Humans[MESH]|Immunohistochemistry[MESH]|Incidence[MESH]|Liver Neoplasms/*diagnosis/*epidemiology/surgery[MESH]|Magnetic Resonance Imaging[MESH]|Male[MESH]|Mexico/epidemiology[MESH]|Middle Aged[MESH]|Neoplasm Staging[MESH]|Prognosis[MESH]|Risk Assessment[MESH]|Risk Factors[MESH]|Sex Distribution[MESH]|Survival Analysis[MESH] |
