Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
 free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
 free
 free
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
Alvimopan, for postoperative ileus following bowel resection: a pooled analysis of phase III studies Delaney CP; Wolff BG; Viscusi ER; Senagore AJ; Fort JG; Du W; Techner L; Wallin BAnn Surg 2007[Mar]; 245 (3): 355-63OBJECTIVE: To obtain further analysis regarding specific outcomes and alvimopan doses in bowel resection (BR) patients. SUMMARY BACKGROUND DATA: Although postoperative ileus (POI) is common after BR, there is currently no recognized treatment or prevention available. Alvimopan, a novel, peripherally active mu-opioid receptor antagonist, accelerated GI recovery after BR or hysterectomy in 3 phase III trials. METHODS: A pooled retrospective subset analysis of BR patients in alvimopan phase III trials was performed. Randomized BR patients received alvimopan 6 mg (n = 397), 12 mg (n = 413), or placebo (n = 402) >or=2 hours before surgery and twice daily until hospital discharge for |*Digestive System Surgical Procedures[MESH]|Clinical Trials, Phase III as Topic[MESH]|Gastrointestinal Agents/administration & dosage/*therapeutic use[MESH]|Humans[MESH]|Ileus/*drug therapy/etiology[MESH]|Intestine, Large/surgery[MESH]|Intestine, Small/surgery[MESH]|Piperidines/administration & dosage/*therapeutic use[MESH]|Postoperative Complications/drug therapy[MESH]|Proportional Hazards Models[MESH]|Randomized Controlled Trials as Topic[MESH]|Receptors, Opioid, mu/*antagonists & inhibitors[MESH] |
