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Evaluation and differential diagnosis of marked, persistent eosinophilia Nutman TBImmunol Allergy Clin North Am 2007[Aug]; 27 (3): 529-49Hypereosinophilic syndromes (HES) are a group of heterogeneous disorders many of which remain ill-defined. By definition, the HES must be distinguished from other disorders with persistently elevated eosinophilia with a defined cause. Although marked eosinophilia worldwide is most commonly caused by helminth (worm) infections, the diagnostic approach must include noninfectious (nonparasitic) causes of marked eosinophilia as well.|*Eosinophilia/diagnosis/etiology/physiopathology[MESH]|Diagnosis, Differential[MESH]|Eosinophils/*physiology[MESH]|Humans[MESH] |
