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Transposon mediated transgenesis in a marine invertebrate chordate: Ciona intestinalis Sasakura Y; Oogai Y; Matsuoka T; Satoh N; Awazu SGenome Biol 2007[]; 8 Suppl 1 (Suppl 1): S3Achievement of transposon mediated germline transgenesis in a basal chordate, Ciona intestinalis, is discussed. A Tc1/mariner superfamily transposon, Minos, has excision and transposition activities in Ciona. Minos enables the creation of stable transgenic lines, enhancer detection, and insertional mutagenesis.|*Gene Transfer Techniques[MESH]|Animals[MESH]|Ciona intestinalis/*genetics[MESH]|DNA Transposable Elements/*genetics[MESH]|Enhancer Elements, Genetic[MESH]|Genome[MESH]|Mutagenesis, Insertional[MESH] |
