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Outpatient Long-term Intensive Therapy for Alcoholics (OLITA): a successful biopsychosocial approach to the treatment of alcoholism Krampe H; Stawicki S; Hoehe MR; Ehrenreich HDialogues Clin Neurosci 2007[]; 9 (4): 399-412Alcohol dependence is a frequent, chronic, relapsing, and incurable disease with enormous societal costs. Thus, alcoholism therapy and research into its outcome are of major importance for public health. The present article will: (i) give a brief overview of the epidemiology, pathogenesis, and treatment outcomes of alcohol dependence; (ii) introduce the basic principles of outpatient long-term therapy of alcohol-dependent patients; and (iii) discuss in detail process-outcome research on Outpatient Long-term Intensive Therapy for Alcoholics (OLITA). This successful biopsychosocial approach to the treatment of alcoholism shows a 9-year abstinence rate of over 50%, a re-employment rate of 60%, and a dramatic recovery from comorbid depression, anxiety disorders, and physical sequelae. The outcome data are empirically based on treatment processes that have proven high predictive validity and give concrete information about where to focus the therapeutic efforts. Thus, process-outcome research on OLITA can serve for the development of new therapeutic guidelines on adapting individual relapse prevention strategies.|*Outpatients[MESH]|Adult[MESH]|Alcoholism/complications/epidemiology/etiology/*therapy[MESH]|Female[MESH]|Humans[MESH]|Longitudinal Studies[MESH]|Male[MESH]|Middle Aged[MESH]|Personality Disorders/etiology[MESH]|Psychotherapy/*methods[MESH]|Recovery of Function[MESH]|Severity of Illness Index[MESH]|Surveys and Questionnaires[MESH]|Treatment Outcome[MESH] |