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l�ll Myelodysplastic syndrome with isolated 5q deletion (5q- syndrome) A clonal stem cell disorder characterized by defective ribosome biogenesis Cazzola MHaematologica 2008[Jul]; 93 (7): 967-72�|*Chromosome Deletion[MESH]|*Chromosomes, Human, Pair 5[MESH]|Adult[MESH]|Blood Platelets/metabolism[MESH]|Chemistry, Pharmaceutical/methods[MESH]|Clinical Trials as Topic[MESH]|Humans[MESH]|In Situ Hybridization, Fluorescence[MESH]|Karyotyping[MESH]|Lenalidomide[MESH]|Male[MESH]|Myelodysplastic Syndromes/*drug therapy/*genetics[MESH]|Stem Cells/cytology[MESH]|Syndrome[MESH]|Thalidomide/analogs & derivatives/therapeutic use[MESH] |