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Phosphoproteomics: unraveling the signaling web Huang PH; White FMMol Cell 2008[Sep]; 31 (6): 777-81In recent years, phosphoproteomic technologies have increased our understanding of cellular signaling networks. Here, we frame recent phosphoproteomics-based advances in the context of the DNA damage response and ErbB receptor family signaling and offer a perspective on how the molecular insights arising from the integration of such proteomic approaches might be used for clinical applications.|*Proteomics[MESH]|*Signal Transduction[MESH]|Animals[MESH]|DNA Damage[MESH]|Humans[MESH]|Phosphoproteins/*metabolism[MESH]|Receptor Protein-Tyrosine Kinases/metabolism[MESH] |
