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lüll Molecular properties, functions, and potential applications of NAD kinases Shi F; Li Y; Li Y; Wang XActa Biochim Biophys Sin (Shanghai) 2009[May]; 41 (5): 352-61NAD kinase catalyzes the phosphorylation of NAD(H) to form NADP(H), using ATP as phosphoryl donor. It is the only key enzyme leading to the de novo NADP(+)/NADPH biosynthesis. Coenzymes such as NAD(H) and NADP(H) are known for their important functions. Recent studies have partially demonstrated that NAD kinase plays a crucial role in the regulation of NAD(H)/NADP(H) conversion. Here, the molecular properties, physiologic functions, and potential applications of NAD kinase are discussed.|Amino Acid Sequence[MESH]|Anti-Bacterial Agents/pharmacology[MESH]|Bacterial Proteins/antagonists & inhibitors/genetics/*metabolism[MESH]|Models, Biological[MESH]|Molecular Sequence Data[MESH]|Molecular Structure[MESH]|NAD/chemistry/*metabolism[MESH]|NADP/chemistry/*metabolism[MESH]|Phosphotransferases (Alcohol Group Acceptor)/antagonists & inhibitors/genetics/*metabolism[MESH]|Sequence Homology, Amino Acid[MESH] |