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Letting go: modification of cell adhesion during apoptosis Suzanne M; Steller HJ Biol 2009[]; 8 (5): 49Apoptosis appears to be a carefully orchestrated process for the ordered dismantling of cells. A recent paper in BMC Developmental Biology shows that the disassembly of adherens junctions during apoptosis in Drosophila is progressive and requires the amino-terminal cleavage of the beta-catenin Armadillo by the apoptotic effector caspase DrICE.|*Apoptosis[MESH]|Adherens Junctions/metabolism[MESH]|Animals[MESH]|Armadillo Domain Proteins/metabolism[MESH]|Caspases/metabolism[MESH]|Cell Adhesion[MESH]|Drosophila Proteins/metabolism[MESH]|Drosophila melanogaster[MESH]|Epithelial Cells/physiology[MESH]|Transcription Factors/metabolism[MESH] |
