Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
 free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
 free
 free
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
Early events in Kaposi s sarcoma-associated herpesvirus infection of target cells Chandran BJ Virol 2010[Mar]; 84 (5): 2188-99Kaposi's sarcoma-associated herpesvirus (KSHV), the most recently identified member of the herpesvirus family, infects a variety of target cells in vitro and in vivo. This minireview surveys current information on the early events of KSHV infection, including virus-receptor interactions, involved envelope glycoproteins, mode of entry, intracellular trafficking, and initial viral and host gene expression programs. We describe data supporting the hypothesis that KSHV manipulates preexisting host cell signaling pathways to allow successful infection. The various signaling events triggered by infection, and their potential roles in the different stages of infection and disease pathogenesis, are summarized.|B-Lymphocytes/metabolism/virology[MESH]|Cells, Cultured[MESH]|DNA, Viral/genetics/metabolism[MESH]|Endothelial Cells/metabolism/virology[MESH]|Focal Adhesion Protein-Tyrosine Kinases/genetics/metabolism[MESH]|Gene Expression Regulation, Viral[MESH]|Herpesviridae Infections/*metabolism[MESH]|Herpesvirus 8, Human/genetics/*metabolism[MESH]|Humans[MESH]|Keratinocytes/metabolism/virology[MESH]|Microtubules/metabolism[MESH]|Monocytes/metabolism/virology[MESH]|Phosphatidylinositol 3-Kinases/genetics/metabolism[MESH]|Signal Transduction/*physiology[MESH]|Viral Envelope Proteins/genetics/metabolism[MESH]|Virus Internalization[MESH]|Virus Latency[MESH]|rhoA GTP-Binding Protein/genetics/metabolism[MESH]|src-Family Kinases/genetics/metabolism[MESH] |
