Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
 free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
 free
 free
Warning: file_get_contents(http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=20009534&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 445
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
Larval midgut destruction in Drosophila: not dependent on caspases but suppressed by the loss of autophagy Denton D; Shravage B; Simin R; Baehrecke EH; Kumar SAutophagy 2010[Jan]; 6 (1): 163-5While most programmed cell death (PCD) in animal development is reliant upon the caspase-dependent apoptotic pathway and subsequent cleavage of caspase substrates, we found that PCD in Drosophila larval midgut occurs normally in the absence of the main components of the apoptotic machinery. However, when some of the components of the autophagic machinery were disrupted, midgut destruction was severely delayed. These studies demonstrate that Drosophila midgut PCD is executed by a novel mechanism where caspases are apparently dispensable, but that requires autophagy.|Animals[MESH]|Autophagy/genetics/*physiology[MESH]|Body Patterning/genetics/*physiology[MESH]|Caspases/genetics/*physiology[MESH]|Cell Death/genetics/physiology[MESH]|Drosophila/genetics/*growth & development/physiology[MESH]|Intestinal Mucosa/metabolism[MESH]|Intestines/*growth & development/physiology[MESH]|Larva/genetics/metabolism/physiology[MESH]|Models, Biological[MESH] |
