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Polysaccharide-modified synthetic polymeric biomaterials Baldwin AD; Kiick KLBiopolymers 2010[]; 94 (1): 128-40This review presents an overview of polysaccharide-conjugated synthetic polymers and their use in tissue-engineered scaffolds and drug-delivery applications. This topic will be divided into four categories: (1) polymeric materials modified with non-mammalian polysaccharides such as alginate, chitin, and dextran; (2) polymers modified with mammalian polysaccharides such as hyaluronan, chondroitin sulfate, and heparin; (3) multi-polysaccharide-derivatized polymer conjugate systems; and (4) polymers containing polysaccharide-mimetic molecules. Each section will discuss relevant conjugation techniques, analysis, and the impact of these materials as micelles, particles, or hydrogels used in in-vitro and in-vivo biomaterial applications.|Animals[MESH]|Biocompatible Materials/*chemistry[MESH]|Biomimetic Materials/chemistry[MESH]|Carbohydrate Conformation[MESH]|Drug Carriers/chemistry[MESH]|Molecular Sequence Data[MESH]|Molecular Structure[MESH]|Polymers/*chemistry[MESH]|Polysaccharides/*chemistry[MESH]|Tissue Engineering[MESH] |