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Cellular sources of tissue factor in endotoxemia and sepsis Pawlinski R; Mackman NThromb Res 2010[Apr]; 125 Suppl 1 (ä): S70-3Sepsis is a systemic host response to infection by pathogenic microorganisms. Activation of the coagulation cascade during endotoxemia and sepsis leads to disseminated intravascular coagulation. This review focuses on tissue factor expression by hematopoietic and non-hematopoietic cells and its contribution to the activation of coagulation during endotoxemia and sepsis.|Animals[MESH]|Antithrombins/chemistry[MESH]|Blood Coagulation[MESH]|Endothelial Cells/chemistry[MESH]|Endotoxemia/*metabolism[MESH]|Hematopoiesis[MESH]|Humans[MESH]|Lipopolysaccharides/chemistry[MESH]|Models, Biological[MESH]|Sepsis/*metabolism[MESH]|Thrombin/chemistry[MESH]|Thromboplastin/*metabolism[MESH] |
