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Is canalization more than just a beautiful idea?Sato K; Siomi HGenome Biol 2010[]; 11 (3): 109The heat-shock protein 90 (Hsp90) is currently thought to buffer eukaryotic cells against perturbations caused by pre-existing cryptic genetic variation. A new study suggests that the buffering function of Hsp90 could instead be due to its repression of de novo transposon-mediated mutagenesis.|*Genetic Variation[MESH]|*Models, Genetic[MESH]|*Phenotype[MESH]|Animals[MESH]|DNA Transposable Elements/*physiology[MESH]|Drosophila/*genetics[MESH]|HSP90 Heat-Shock Proteins/genetics/*physiology[MESH] |
