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Breaking the cycle of medication overuse headache Tepper SJ; Tepper DECleve Clin J Med 2010[Apr]; 77 (4): 236-42When patients who have frequent, disabling migraines take medications to relieve their symptoms, they run the risk that the attacks will increase in frequency to daily or near-daily as a rebound effect comes into play. This pattern, called medication overuse headache, is more likely to happen with butalbital and opioids than with migraine-specific drugs, as partial responses lead to recurrence, repeat dosing, and, eventually, overuse. Breaking the cycle involves weaning the patient from the overused medications, setting up a preventive regimen, and setting strict limits on the use of medications to relieve acute symptoms.|Analgesics, Opioid/administration & dosage/*adverse effects[MESH]|Barbiturates/administration & dosage/*adverse effects[MESH]|Disease Susceptibility[MESH]|Headache Disorders, Secondary/*chemically induced/*prevention & control[MESH]|Humans[MESH]|Migraine Disorders/*drug therapy[MESH]|Patient Education as Topic[MESH]|Recurrence[MESH]|Risk Factors[MESH]|Substance Withdrawal Syndrome[MESH]|Substance-Related Disorders/*prevention & control[MESH]|Terminology as Topic[MESH]|Tryptamines/administration & dosage/*adverse effects[MESH] |
