Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
 free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
 free
 free
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
Autopsy findings after intracranial thrombectomy for acute ischemic stroke: a clinicopathologic study of 5 patients Yin NS; Benavides S; Starkman S; Liebeskind DS; Saver JA; Salamon N; Jahan R; Duckwiler GR; Tateshima S; Vinuela F; Vespa PM; Chute DJ; Vinters HVStroke 2010[May]; 41 (5): 938-47BACKGROUND AND PURPOSE: Endovascular thrombectomy is an increasingly used treatment for arterial occlusion in acute stroke. Various devices (including most extensively the Mechanical Embolus Removal in Cerebral Ischemia [MERCI] Retriever device) have been used for this. METHODS: We review the neuropathologic findings in 5 patients (age range, 59 to 87 years) who died acutely or as late as 38 days after procedures using the MERCI (4 patients) and Penumbra (1 patient) devices were carried out to remove thromboemboli from the middle cerebral artery. Partial recanalization was achieved by thrombectomy in all 5 patients. RESULTS: All patients showed extensive cerebral infarcts, 3 of 5 with clinical hemorrhagic transformations of the infarct or frank intraparenchymal hemorrhage after thrombectomy; in 1 case, this was judged to be at least partly on the basis of concomitant hypertensive microvascular disease. With 1 exception, basal arteries examined in detail by immunohistochemistry showed prominent, although usually nonocclusive (and generally nonulcerated), atheromata, often with significant luminal stenosis. One patient showed a subintimal dissection with resultant occlusion of the middle cerebral artery. CONCLUSIONS: In this highly selected group of patients, the vascular pathological abnormalities affecting basal arteries were variable, but complicated atherosclerosis was a common finding. Extensive irreversible brain necrosis before therapeutic procedures may have contributed to deaths.|*Thrombectomy/mortality[MESH]|Aged[MESH]|Aged, 80 and over[MESH]|Brain Ischemia/drug therapy/mortality/*pathology/*surgery[MESH]|Female[MESH]|Humans[MESH]|Intracranial Thrombosis/drug therapy/mortality/pathology/surgery[MESH]|Male[MESH]|Middle Aged[MESH]|Stroke/drug therapy/mortality/*pathology/*surgery[MESH]|Subarachnoid Hemorrhage/drug therapy/mortality/pathology/surgery[MESH]|Tissue Plasminogen Activator/administration & dosage[MESH] |
