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HIV infection-related tuberculosis: clinical manifestations and treatment Sterling TR; Pham PA; Chaisson REClin Infect Dis 2010[May]; 50 Suppl 3 (ä): S223-30Several aspects of human immunodeficiency virus (HIV) infection-related tuberculosis (TB) and its treatment differ from those of TB in HIV-uninfected persons. The risk of TB and the clinical and radiographic manifestations of disease are primary examples. Antiretroviral therapy has a profound effect on lowering the risk of TB in HIV-infected persons, but it can also be associated with immune reconstitution inflammatory disease and unmasking of previously subclinical disease. There are also differences in treatment of HIV infection-related TB because of overlapping drug toxicities and drug-drug interactions between antiretroviral therapy and anti-TB therapy.|AIDS-Related Opportunistic Infections/*drug therapy/*pathology[MESH]|Anti-HIV Agents/therapeutic use[MESH]|Antitubercular Agents/therapeutic use[MESH]|Drug Interactions[MESH]|HIV Infections/*complications[MESH]|Humans[MESH]|Immune Reconstitution Inflammatory Syndrome[MESH]|Tuberculosis/*drug therapy/*pathology[MESH] |
