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lüll From interstitial cystitis to chronic pelvic pain Persu C; Cauni V; Gutue S; Blaj I; Jinga V; Geavlete PJ Med Life 2010[Apr]; 3 (2): 167-74There are still many things to be found out about interstitial cystitis/painful bladder syndrome (IC/PBS) because the pathological processes underlying the condition are not yet elucidated, biological markers of the condition are not yet available, and the type and severity of symptoms can vary, so, clearly defining the condition is not yet possible. For example, it is not clearly understood whether IC/PBS represents a systemic disease, if it is localized in the bladder, or if it was initially localized in the bladder and it later evolved into a systemic disease. This condition is best managed by using a multidisciplinary approach. Management requires a good integration and knowledge of all pelvic organ systems and other systems including musculoskeletal, neurologic, and psychiatric systems.|Biomarkers/urine[MESH]|Botulinum Toxins, Type A/administration & dosage[MESH]|Cystitis, Interstitial/diagnosis/*physiopathology/therapy[MESH]|Female[MESH]|Humans[MESH]|Male[MESH]|Oligonucleotide Array Sequence Analysis[MESH]|Pelvic Pain/*physiopathology/therapy[MESH]|Pentosan Sulfuric Polyester/administration & dosage[MESH] |