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lüll Prediction of recovery time from hypoglycemia in patients with insulin overdose Ohyama T; Saisho Y; Muraki A; Kawai T; Itoh HEndocr J 2011[]; 58 (7): 607-11Insulin overdose results in prolonged hypoglycemia. We hypothesized that if a huge amount of insulin is subcutaneously injected, the duration of hypoglycemia depends on the dose of insulin rather than the type of insulin. We conducted a literature review of insulin overdose and 33 cases were included in this study. We assessed the correlation between recovery time from hypoglycemia and insulin dose. As a result, there was a significant correlation between recovery time from hypoglycemia and insulin dose (r=0.88, p<0.0001) and this correlation was expressed as y=0.045x; where y is time (h) and x is insulin dose (U), corresponding to that if 1000 U insulin is injected, hypoglycemia will persist for ~45 h. This equation may be useful to predict the duration of glucose supplementation for treatment of insulin overdose.|Adult[MESH]|Aged[MESH]|Drug Overdose[MESH]|Female[MESH]|Humans[MESH]|Hypoglycemia/*chemically induced[MESH]|Insulin/administration & dosage/*poisoning[MESH]|Male[MESH]|Middle Aged[MESH]|Recovery of Function[MESH]|Regression Analysis[MESH]|Young Adult[MESH] |