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Contrast-enhanced multiple-phase imaging features in hepatic epithelioid hemangioendothelioma Chen Y; Yu RS; Qiu LL; Jiang DY; Tan YB; Fu YBWorld J Gastroenterol 2011[Aug]; 17 (30): 3544-53AIM: To investigate and review the contrast-enhanced multiple-phase computed tomography (CEMP CT) and magnetic resonance imaging (MRI) findings in patients with pathologically confirmed hepatic epithelioid hemangioendothelioma (HEHE). METHODS: Findings from imaging examinations in 8 patients (5 women and 3 men) with pathologically confirmed HEHE were retrospectively reviewed (CT images obtained from 7 patients and MR images obtained from 6 patients). The age of presentation varied from 27 years to 60 years (average age 39.8 years). RESULTS: There were two types of HEHE: multifocal type (n = 7) and diffuse type (n = 1). In the multifocal-type cases, there were 74 lesions on CT and 28 lesions on MRI with 7 lesions found with diffusion weighted imaging; 18 (24.3%) of 74 lesions on plain CT and 26 (92.9%) of 28 lesions on pre-contrast MRI showed the target sign. On CEMP CT, 28 (37.8%) of 74 lesions appeared with the target sign and a progressive-enhancement rim and 9 (12.2%) of 74 lesions displayed progressive enhancement, maintaining a state of persistent enhancement. On CEMP MRI, 27 (96.4%) of 28 lesions appeared with the target sign with a progressive-enhancement rim and 28 (100%) of 28 lesions displayed progressive-enhancement, maintaining a state of persistent enhancement. In the diffuse-type cases, an enlarged liver was observed with a large nodule appearing with persistent enhancement on CEMP CT and MRI. CONCLUSION: The most important imaging features of HEHE are the target sign and/or progressive enhancement with persistent enhancement on CEMP CT and MRI. MRI is advantageous over CT in displaying these imaging features.|Adult[MESH]|Contrast Media/metabolism[MESH]|Female[MESH]|Hemangioendothelioma, Epithelioid/*diagnostic imaging/*pathology[MESH]|Humans[MESH]|Liver Neoplasms/*diagnostic imaging/*pathology[MESH]|Liver/diagnostic imaging/pathology[MESH]|Magnetic Resonance Imaging/*methods[MESH]|Male[MESH]|Middle Aged[MESH]|Retrospective Studies[MESH]|Tomography, X-Ray Computed/*methods[MESH] |
